{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:19:43Z","timestamp":1747149583591,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T00:00:00Z","timestamp":1645401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Since nearly one\u2010fifth of US adults have a psychiatric disorder, genetic counselors (GCs) will see many patients with these indications. However, GCs\u2019 reports of inadequate preparation and low confidence in providing care for patients with psychiatric disorders can limit their ability to meet patient's needs. How frequently psychiatric disorders present in GC sessions is currently unclear. Here, we used deidentified electronic health records (EHR) to estimate the prevalence of 16 psychiatric disorders. In 7,155 GC patients, 34% had a diagnostic code associated with a psychiatric disorder; 23% with anxiety\/phobic disorders; 21% with mood disorder\/depression; 5% with attention deficit hyperactivity disorder (ADHD); and 1% with psychotic disorders. Compared to 415,709 demographically matched controls, GC patients showed a significantly higher prevalence of psychiatric disorders (GC prevalence: 34%, matched prevalence: 30%, <jats:italic>p<\/jats:italic>\u2010value\u00a0&lt;\u00a00.0001) driven predominantly by anxiety disorder, major depressive disorder, generalized anxiety disorder, and ADHD. Within GC specialties (prenatal: <jats:italic>n<\/jats:italic>\u00a0=\u00a02,674, cancer: <jats:italic>n<\/jats:italic>\u00a0=\u00a01,474, pediatric: <jats:italic>n<\/jats:italic>\u00a0=\u00a0465), only pediatric GC patients showed a significant increase in psychiatric disorder prevalence overall (pediatric GC prevalence: 28%, matched prevalence: 13%, <jats:italic>p<\/jats:italic>\u2010value\u00a0&lt;\u00a00.0001). However, significant evidence of increased prevalence existed for generalized anxiety disorder (prenatal GC prevalence 6.4%, matched prevalence: 4.9%, <jats:italic>p<\/jats:italic>\u2010value\u00a0&lt;\u00a00.0001), anxiety disorders (cancer GC prevalence: 26%, matched prevalence: 21%, <jats:italic>p<\/jats:italic>\u2010value\u00a0&lt;\u00a00.0001 and pediatric GC prevalence: 12%, matched prevalence: 5.5%), and ADHD (pediatric GC prevalence: 18%, matched prevalence: 7.9%, <jats:italic>p<\/jats:italic>\u2010value\u00a0&lt;\u00a00.0001). These results highlight the need for additional guidance around care for patients with psychiatric disorders and the value of EHR\u2010based research in genetic counseling.<\/jats:p>","DOI":"10.1002\/jgc4.1565","type":"journal-article","created":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T06:54:13Z","timestamp":1645512853000},"page":"1008-1015","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Leveraging electronic health records to inform genetic counseling practice surrounding psychiatric disorders"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7053-6500","authenticated-orcid":false,"given":"Lucas D.","family":"Richter","sequence":"first","affiliation":[{"name":"Division of Genetic Medicine Department of Medicine Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodore J.","family":"Morley","sequence":"additional","affiliation":[{"name":"Division of Genetic Medicine Department of Medicine Vanderbilt University Medical Center  Nashville Tennessee USA"},{"name":"Vanderbilt Genetics Institute Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gillian W.","family":"Hooker","sequence":"additional","affiliation":[{"name":"Vanderbilt Genetics Institute Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holly L.","family":"Peay","sequence":"additional","affiliation":[{"name":"RTI International  Research Triangle Park North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy J.","family":"Cox","sequence":"additional","affiliation":[{"name":"Division of Genetic Medicine Department of Medicine Vanderbilt University Medical Center  Nashville Tennessee USA"},{"name":"Vanderbilt Genetics Institute Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas M.","family":"Ruderfer","sequence":"additional","affiliation":[{"name":"Division of Genetic Medicine Department of Medicine Vanderbilt University Medical Center  Nashville Tennessee USA"},{"name":"Vanderbilt Genetics Institute Vanderbilt University Medical Center  Nashville Tennessee USA"},{"name":"Department of Biomedical Informatics Vanderbilt Genetics Institute Vanderbilt University Medical Center  Nashville Tennessee USA"},{"name":"Department of Psychiatry and Behavioral Sciences Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/ps.2007.58.2.254"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cge.12551"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897\u2010017\u20100147\u2010y"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1108\/IJHRH\u201005\u20102017\u20100020"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2749"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897\u2010013\u20109594\u20102"},{"issue":"3","key":"e_1_2_9_8_1","first-page":"168","article-title":"Lifetime prevalence and age\u2010of\u2010onset distributions of mental disorders in the world health organization\u2019s world mental health survey initiative","volume":"6","author":"Kessler R. C.","year":"2007","journal-title":"World Psychiatry"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897\u2010017\u20100146\u2010z"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2020.2159"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.830"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291709991036"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000210096"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(13)70011\u20105"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010021\u201001356\u2010z"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897\u2010013\u20109685\u20100"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl\u20102015\u2010207488"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2008.89"},{"key":"e_1_2_9_19_1","first-page":"970","article-title":"Automatic genetic risk assessment calculation using breast cancer family history data from the EHR compared to self\u2010report","volume":"2018","author":"Sin M.","year":"2018","journal-title":"AMIA Annual Symposium Proceedings"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyu038"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468\u20102667(18)30203\u20102"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11050365"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12916"}],"container-title":["Journal of Genetic Counseling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgc4.1565","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jgc4.1565","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgc4.1565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T10:21:36Z","timestamp":1692872496000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgc4.1565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,21]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1002\/jgc4.1565"],"URL":"https:\/\/doi.org\/10.1002\/jgc4.1565","archive":["Portico"],"relation":{},"ISSN":["1059-7700","1573-3599"],"issn-type":[{"type":"print","value":"1059-7700"},{"type":"electronic","value":"1573-3599"}],"subject":[],"published":{"date-parts":[[2022,2,21]]},"assertion":[{"value":"2021-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}