{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T12:07:03Z","timestamp":1749211623563,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T00:00:00Z","timestamp":1646697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100010237","name":"National Society of Genetic Counselors","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010237","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Bicuspid aortic valve (BAV) is the most common congenital heart defect, which can cause severe cardiac complications. BAVs cluster in families and demonstrate high heritability. Cardiac screening for first\u2010degree relatives of individuals with a BAV is recommended. This retrospective two\u2010group study evaluated the impact of cardiovascular genetic counseling provided by a board\u2010certified genetic counselor on parent\u2010reported outcomes by comparing parental responses of those who received genetic counseling by a genetic counselor (GC group) for family history of BAV to those who did not (non\u2010GC group). A retrospective chart review from May 2016 to June 2019 identified 133 pediatric patients with an isolated BAV. Parents of eligible probands were invited to complete an online survey assessing genetics knowledge, empowerment (Genomics Outcome Scale), and familial uptake of cardiac screening. Surveys were completed by 38\/97 (39%) parents in the non\u2010GC group and 20\/36 (56%) parents in the GC group. The median genetics knowledge score was not significantly different between the two groups (GC group: 8, range 3\u201311 out of a maximum possible of 12; non\u2010GC group: 7, range 2\u201311; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.08). The mean empowerment score was not significantly different between the two groups (GC group: mean 24.6, <jats:italic>SD<\/jats:italic> 2.2; non\u2010GC group: mean 23.2, <jats:italic>SD<\/jats:italic> 3.5; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.06). The uptake of cardiac screening was significantly higher in the GC group with 39\/59 (66%) total first\u2010degree relatives reported as having been screened compared with 36\/91 (40%) in the non\u2010GC group (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.002). Parent\u2010reported outcomes in our study suggest that receiving genetic counseling by a board\u2010certified genetic counselor significantly increased familial uptake of cardiac screening for first\u2010degree relatives of pediatric patients with a BAV. Studies with larger sample sizes are needed to confirm the findings of this study; however, a referral to a genetic counselor should be considered for patients with a BAV.<\/jats:p>","DOI":"10.1002\/jgc4.1570","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T06:15:26Z","timestamp":1646806526000},"page":"965-975","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Retrospective comparison of parent\u2010reported genetics knowledge, empowerment, and familial uptake of cardiac screening between parents who received genetic counseling by a certified genetic counselor and those who did not: A single US academic medical center study"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6038-2408","authenticated-orcid":false,"given":"Bailey","family":"Hancock","sequence":"first","affiliation":[{"name":"Division of Human Genetics Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"College of Medicine University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin M.","family":"Miller","sequence":"additional","affiliation":[{"name":"Division of Human Genetics Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"College of Medicine University of Cincinnati  Cincinnati Ohio USA"},{"name":"Heart Institute Cincinnati Children\u2019s Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Parrott","sequence":"additional","affiliation":[{"name":"Heart Institute Cincinnati Children\u2019s Hospital Medical Center  Cincinnati Ohio USA"},{"name":"Genome Medical  San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn Nicole","family":"Weaver","sequence":"additional","affiliation":[{"name":"Division of Human Genetics Cincinnati 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