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Little is known about the experience of receiving an NIPT result indicating an increased chance of SCA. This study aimed to explore the experiences of people who received this result and their perspectives on the information, care, and support they received from healthcare practitioners (HCPs). Semi\u2010structured interviews were conducted with people who received an NIPT result indicating an increased chance of SCA and continued their pregnancy. Most participants only had contact with a genetic counselor after receiving their result. Transcribed data were analyzed using rigorous thematic analysis to identify important patterns and themes. Participants (18 women, 2 male partners) described embarking on NIPT, primarily based on advice from their HCP and without much consideration. Consequently, participants expressed feeling unprepared for the unanticipated complexity of their NIPT result and were faced with making a time\u2010sensitive decision about a condition they had not previously considered. While more pre\u2010test information was desired, timely access to genetic counseling post\u2010test assisted with adjustment to the result. These findings suggest that routinization of NIPT may be compromising informed decision\u2010making, resulting in unpreparedness for an increased chance result. Given the increasing uptake and expanding scope of NIPT, resources should be dedicated to educating HCPs offering NIPT and ensuring timely access to genetic counseling post\u2010result. With appropriate funding, genetics services may be able to play a central role in offering information and support to both people who undertake NIPT and their HCPs ordering the testing. Implementing a publicly funded screening program in Australia could assist with standardizing prenatal screening care pathways and consequently better access to appropriate resources.<\/jats:p>","DOI":"10.1002\/jgc4.1635","type":"journal-article","created":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T04:07:35Z","timestamp":1663387655000},"page":"213-223","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Experiences of receiving an increased chance of sex chromosome aneuploidy result from non\u2010invasive prenatal testing in Australia: \u201cA more complicated scenario than what I had ever realized\u201d"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7744-6471","authenticated-orcid":false,"given":"Miranda F.","family":"Lewit\u2010Mendes","sequence":"first","affiliation":[{"name":"Department of Paediatrics University of Melbourne  Melbourne Victoria 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