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While PGT\u2010M is primarily used to avoid implanting embryos with a monogenic condition, patients can request to transfer an embryo with the monogenic condition (positive embryo transfer), especially in cases where an IVF cycle results in no unaffected embryos. Transferring embryos with known disease\u2010causing variants raises ethical concerns. There is limited understanding about how stakeholders in the assisted reproductive technology (ART) field approach these issues. In this study, genetic counselors were sent a survey to gather insight into their views about transferring embryos with different monogenic conditions. <jats:italic>N<\/jats:italic>\u2009=\u200999 genetic counselors completed the survey, 22 of whom had experience with patients requesting or deciding to transfer an embryo with a monogenic condition (positive embryo transfer experience). Most participants, including those with positive embryo transfer experience, were supportive of positive embryo transfer, regardless of the genetic condition. While participating genetic counselors were largely supportive of all patient decisions, they reported increased moral uneasiness around transferring embryos with life\u2010limiting monogenic conditions, such as Huntington's disease. Further investigation into the experiences of genetic counselors who have experienced positive embryo transfer requests in practice can help delineate the ethical questions that ART providers face in this context and clarify how genetic counselors can contribute to establishing guidelines in the ART field.<\/jats:p>","DOI":"10.1002\/jgc4.1923","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T06:38:53Z","timestamp":1716532733000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Transfer of embryos with positive PGT\u2010M results: Genetic Counselors' perspectives and ethical considerations"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0561-4788","authenticated-orcid":false,"given":"Silvia","family":"Gunderson","sequence":"first","affiliation":[{"name":"Division of Graduate Medical Sciences Boston University Chobanian &amp; Avedisian School of Medicine  Boston Massachusetts USA"},{"name":"Icahn School of Medicine at Mount Sinai  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1415-8656","authenticated-orcid":false,"given":"Jazmine","family":"Gabriel","sequence":"additional","affiliation":[{"name":"Division of Graduate Medical Sciences Boston University Chobanian &amp; Avedisian School of Medicine  Boston Massachusetts USA"},{"name":"Department of Population Health Sciences Research Institute, Geisinger  Danville Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,24]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003714"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5762"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897\u2010014\u20109728\u20101"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.05.048"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815\u2010019\u201001538\u20102"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41431\u2010021\u201000962\u20102"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1037\/h0085885"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1015275022199"},{"key":"e_1_2_12_10_1","first-page":"1","volume-title":"GeneReviews\u00ae","author":"Caron N. 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