{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:28:30Z","timestamp":1790011710052,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Genetic testing for breast cancer susceptibility genes (BRCA1\/2) plays a pivotal role in risk assessment and preventive interventions. However, individuals' awareness, knowledge, and attitudes toward genetic testing can vary across different societies. This study focuses on understanding Turkish women's knowledge, perceptions, and attitudes toward BRCA1\/2 testing, considering demographic factors and awareness. In this cross\u2010sectional study, 301 Turkish participants, including breast\/ovarian cancer patients and their first\u2010degree relatives, were surveyed. Information on sociodemographics, cancer history, awareness, knowledge, and perceptions was collected. The study aimed to assess knowledge levels about breast cancer inheritance and BRCA1\/2 testing, describe perspectives about testing in women with a family history of breast or ovarian cancer, and determine associations between knowledge, personal factors, anxiety, and genetic testing perspectives. Results showed a wide range in correct responses (31.6%\u201396.7%) for knowledge items. No significant relationship between knowledge levels and positive perception was observed. However, participants answering a specific question incorrectly showed higher negative perceptions. While most participants recognized the benefits of genetic testing, concerns centered around passing the genes to future generations. Participants who were younger, more educated, had higher income, were employed, at an earlier disease stage, and were social media users demonstrated more positive attitudes. Negative perceptions were higher among younger patients, physicians, and healthcare professionals. Interestingly, anxiety in cancer patients did not correlate with either positive or negative perceptions. In conclusion, this study identifies participant\u2010related factors influencing perceptions of hereditary genetic tests. Understanding these factors and addressing associated issues can enhance the utilization of genetic testing and promote preventive oncology applications.<\/jats:p>","DOI":"10.1002\/jgc4.1974","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T11:43:44Z","timestamp":1728301424000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The effect of knowledge and person\u2010related factors on breast cancer susceptibility genes (BRCA1\/2) testing perception in Turkish women"],"prefix":"10.1002","volume":"34","author":[{"given":"Mertcan","family":"Nabioglu","sequence":"first","affiliation":[{"name":"Department of Medical Internal Medicine, School of Medicine Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tulay","family":"Kus","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, School of Medicine Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4199-6943","authenticated-orcid":false,"given":"Gokmen","family":"Aktas","sequence":"additional","affiliation":[{"name":"Gaziantep Medical Point Private Hospital  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konca","family":"Ahmet","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, School of Medicine Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hac\u0131","family":"Arak","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, School of Medicine Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.1066"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13187\u2010014\u20100724\u20109"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgc4.1189"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1005416203239"},{"key":"e_1_2_10_6_1","first-page":"369","article-title":"Attitudes and interest in genetic testing for breast and ovarian cancer susceptibility in diverse groups of women in western Washington","volume":"8","author":"Durfy S. 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