{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T12:26:33Z","timestamp":1776515193588,"version":"3.51.2"},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The demand for genetic testing and counseling services continues to grow as there is a utility to guide diagnosis and treatment for a range of genetic conditions. Genetic counseling (GC) is a medical practice that provides information and counseling to patients and relatives at risk of recurrence of a genetic disease and helps them understand and adapt to the medical, psychological, and familial implications of the genetic information of the disease. Health professionals working in this field need reliable measurement tools to evaluate the results of their interventions, intending to ensure quality service improvements and planning successful disease management strategies. The Genetic Counseling Outcome Scale (GCOS\u201024) is a brief self\u2010reported questionnaire of 24 questions administered to assess GC interventions and the outcomes of the use of these services in patients and caregivers of individuals with genetic diseases. It has been translated and validated in many languages, but not in the Greek language, despite the increased need for GC services in Greece. Thus, the questionnaire was translated into Modern Greek, and the reverse translation method was followed. 257 people participated in the research (63.6% women, 67.8% between 20 and 40\u2009years, 45.9% University education of a high educational level). The construct validity of the questionnaire was examined through exploratory factor analysis and internal consistency through Cronbach's alpha. A significant difference in GCOS from the original scale is the fewer items\u201419 as opposed to 24. Greek GCOS is constructed of a two\u2010factor structure and is a reliable tool (<jats:italic>\u03b1<\/jats:italic>\u2009=\u20090.79) for assessing patient empowerment in GC. With empowerment serving as an end measure, as it is focused on patient\u2010centered care, this study adds to the international validation process of the GCOS\u201024 with the eventual objective of utilizing this instrument as a PROM to assess and enhance the services of GC in diverse clinical genetics settings.<\/jats:p>","DOI":"10.1002\/jgc4.70068","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T06:45:05Z","timestamp":1750401905000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A preliminary adaptation and validation of the genetic counseling outcome scale (<scp>GCOS<\/scp>\u201024) for use in Greece"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1262-0747","authenticated-orcid":false,"given":"Marina","family":"Makri","sequence":"first","affiliation":[{"name":"1st Department of Neurology, Faculty of Health Sciences, School of Medicine Aristotle University of Thessaloniki  Thessaloniki Greece"},{"name":"Greek Association of Alzheimer Disease and Related Disorders  Thessaloniki Greece"},{"name":"Laboratory of Neurodegenerative Disease, Center for Interdisciplinary Research and Innovation, (CIRI\u2014AUTh), Balkan Center Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3588-6493","authenticated-orcid":false,"given":"Anthoula","family":"Palasidou","sequence":"additional","affiliation":[{"name":"1st Department of Neurology, Faculty of Health Sciences, School of Medicine Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Despoina","family":"Moraitou","sequence":"additional","affiliation":[{"name":"Laboratory of Neurodegenerative Disease, Center for Interdisciplinary Research and Innovation, (CIRI\u2014AUTh), Balkan Center Aristotle University of Thessaloniki  Thessaloniki Greece"},{"name":"Department of Cognition, Brain and Behavior, School of Psychology Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Tegos","sequence":"additional","affiliation":[{"name":"1st Department of Neurology, Faculty of Health Sciences, School of Medicine Aristotle University of Thessaloniki  Thessaloniki Greece"},{"name":"Laboratory of Neurodegenerative Disease, Center for Interdisciplinary Research and Innovation, (CIRI\u2014AUTh), Balkan Center Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liana","family":"Fidani","sequence":"additional","affiliation":[{"name":"Department of Medical Biology\u2010Genetics, Faculty of Health Sciences, School of Medicine Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalini","family":"Tsolaki","sequence":"additional","affiliation":[{"name":"1st Department of Neurology, Faculty of Health Sciences, School of Medicine Aristotle University of Thessaloniki  Thessaloniki Greece"},{"name":"Greek Association of Alzheimer Disease and Related Disorders  Thessaloniki Greece"},{"name":"Laboratory of Neurodegenerative Disease, Center for Interdisciplinary Research and Innovation, (CIRI\u2014AUTh), Balkan Center Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41431\u2010018\u20100252\u2010x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpam.2015.12.002"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0272\u20107358(88)90050\u20105"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/\/0022\u2010006x.56.6.893"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650\u2010197501000\u201000002"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096\u20108628(20000918)94:3<189::AID\u2010AJMG3>3.0.CO;2\u2010E"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f167"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgc4.1319"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjqs\u20102013\u2010002524"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913\u2010015\u20100907\u2010z"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897\u2010017\u20100079\u20106"},{"key":"e_1_2_11_13_1","volume-title":"Getting the most out of PROMs: Putting health outcomes at the heart of NHS decision\u2010making","author":"Devlin N. 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Jahrestagung des Netzwerks Evidenzbasierte Medizin.https:\/\/doi.org\/10.3205\/23EBM076"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0141076816677856"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijn.12715"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgc4.1452"},{"key":"e_1_2_11_24_1","unstructured":"L\u00f8vik I. K.(2022).Adaptive translation of the genetic counselling outcome scale \u2013 A patient\u2010reported outcome measure for application in genetic counselling in Norway. Thesis for: Master of Health Science. 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