{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:04:48Z","timestamp":1790337888408,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100025520","name":"Medical Research Future Fund","doi-asserted-by":"publisher","award":["GHFM76765"],"award-info":[{"award-number":["GHFM76765"]}],"id":[{"id":"10.13039\/501100025520","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004239","name":"Politechnika Pozna\u0144ska","doi-asserted-by":"publisher","award":["2008300"],"award-info":[{"award-number":["2008300"]}],"id":[{"id":"10.13039\/501100004239","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    While whole exome sequencing (WES) in pregnancy for fetal structural anomalies (FSA) has become increasingly feasible in Australia, parents' experiences of undergoing WES for FSA are poorly understood. This study explored the experiences of participants undergoing prenatal WES for FSA in Australia. Forty expectant parents from 28 parent\u2013fetus trios were interviewed prior to receiving WES results, and interviews were analyzed using inductive content analysis. Participants consistently expressed a desire for as much information as possible about their unborn child (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200917), describing this as a \u201cquest for knowledge.\u201d The waiting period for results was identified as an especially difficult and emotionally taxing aspect of WES during pregnancy (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200912). Overall, participants reported mostly positive experiences with healthcare professionals, noting the importance of compassionate and supportive care (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200921). Many couples also considered termination of pregnancy as a possible outcome if a diagnosis was confirmed through WES (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200913). These findings suggest that a nuanced understanding of participants' experiences can help guide clinical practice. Improvements may be achieved by expediting testing processes, ensuring supportive and compassionate healthcare interactions, and facilitating sensitive discussions regarding termination of pregnancy if families feel ready to engage with this potential option. The future of genomic sequencing in pregnancy will rely on providing supported access to clinical testing and ensuring laboratories deliver fast, accurate results during this critical period for prospective parents.\n                  <\/jats:p>","DOI":"10.1002\/jgc4.70158","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T06:31:36Z","timestamp":1769495496000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Australian patients' experiences of undergoing whole exome sequencing for fetal structural anomalies prior to receiving results"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8187-1726","authenticated-orcid":false,"given":"Sarah","family":"Long","sequence":"first","affiliation":[{"name":"Neuroscience Research Australia (NeuRA) University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly E.","family":"Evans","sequence":"additional","affiliation":[{"name":"Behavioural Sciences Unit, Discipline of Paediatrics &amp; Child Health, School of Clinical Medicine, Randwick Clinical Campus UNSW Medicine &amp; Health, UNSW  Sydney New South Wales Australia"},{"name":"Kids Cancer Centre Sydney Children's Hospital  Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire E.","family":"Wakefield","sequence":"additional","affiliation":[{"name":"Behavioural Sciences Unit, Discipline of Paediatrics &amp; Child Health, School of Clinical Medicine, Randwick Clinical Campus UNSW Medicine &amp; Health, UNSW  Sydney New South Wales Australia"},{"name":"Division of Quality of Life and Pediatric Palliative Care, Department of Pediatrics Stanford University and Stanford Medicine Children's Health  Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine A.","family":"Kasparian","sequence":"additional","affiliation":[{"name":"Heart and Mind Wellbeing Center, Heart Institute and the Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"McGillivray","sequence":"additional","affiliation":[{"name":"Royal Women's Hospital  Parkville Victoria Australia"},{"name":"Victorian Clinical Genetics Services Murdoch Children's Research Institute  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Roscioli","sequence":"additional","affiliation":[{"name":"Neuroscience Research Australia (NeuRA) University of New South Wales  Sydney New South Wales Australia"},{"name":"New South Wales Health Pathology Randwick Genomics Prince of Wales Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber\u2010Marie","family":"Firriolo","sequence":"additional","affiliation":[{"name":"Behavioural Sciences Unit, Discipline of Paediatrics &amp; Child Health, School of Clinical Medicine, Randwick Clinical Campus UNSW Medicine &amp; Health, UNSW  Sydney New South Wales Australia"},{"name":"Kids Cancer Centre Sydney Children's Hospital  Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayamala","family":"Parmar","sequence":"additional","affiliation":[{"name":"Neuroscience Research Australia (NeuRA) University of New South Wales  Sydney New South Wales Australia"},{"name":"Centre for Economic Impacts of Genomic Medicine Macquarie University  New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Kelada","sequence":"additional","affiliation":[{"name":"Behavioural Sciences Unit, Discipline of Paediatrics &amp; Child Health, School of Clinical Medicine, Randwick Clinical Campus UNSW Medicine &amp; Health, UNSW  Sydney New South Wales Australia"},{"name":"Kids Cancer Centre Sydney Children's Hospital  Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"e_1_2_17_2_1","volume-title":"Enquiry into abortion and reproductive choice in the ACT","author":"ACT Government","year":"2022"},{"key":"e_1_2_17_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.906"},{"key":"e_1_2_17_4_1","volume-title":"Education and training: Census","author":"Australian Bureau of Statistics","year":"2021"},{"key":"e_1_2_17_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2018.30"},{"key":"e_1_2_17_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12298"},{"key":"e_1_2_17_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5464"},{"key":"e_1_2_17_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12332"},{"key":"e_1_2_17_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0890334419830990"},{"key":"e_1_2_17_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20101\u20104939\u20108889\u20101_18"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.midw.2021.103095"},{"key":"e_1_2_17_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884\u2010022\u201004770\u20104"},{"key":"e_1_2_17_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.34399"},{"key":"e_1_2_17_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12501"},{"key":"e_1_2_17_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2017.10.003"},{"key":"e_1_2_17_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-30199-6"},{"key":"e_1_2_17_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.13608"},{"key":"e_1_2_17_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.13936"},{"key":"e_1_2_17_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/hex.12664"},{"key":"e_1_2_17_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732315617444"},{"key":"e_1_2_17_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4698"},{"key":"e_1_2_17_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.6537"},{"key":"e_1_2_17_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.6115"},{"key":"e_1_2_17_24_1","volume-title":"Termination of Pregnancy Law Reform Act","author":"Northern Territory Government","year":"2017"},{"key":"e_1_2_17_25_1","unstructured":"NSW Government. 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