{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:59:39Z","timestamp":1787759979492,"version":"build-2784847793"},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T00:00:00Z","timestamp":1554249600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gen and Family Med"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this report, we present the successful treatment of five consecutive cases of premenopausal women suffering from severe menstrual migraine with tokishakuyakusan (<jats:styled-content style=\"fixed-case\">TSS<\/jats:styled-content>). Two patients were complicated by tension\u2010type headache (<jats:styled-content style=\"fixed-case\">TTH<\/jats:styled-content>), and another patient was by medication overuse headache (<jats:styled-content style=\"fixed-case\">MOH<\/jats:styled-content>). The effects of triptans were limited in all of them. After starting <jats:styled-content style=\"fixed-case\">TSS<\/jats:styled-content>, they showed dramatic improvement in the severity and frequency of their attacks. The patients with <jats:styled-content style=\"fixed-case\">TTH<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MOH<\/jats:styled-content> also showed dramatic improvement in their symptoms. <jats:styled-content style=\"fixed-case\">TSS<\/jats:styled-content> could be a promising alternative choice for patients with intractable menstruation\u2013related headaches that are refractory to conventional treatments, including triptans.<\/jats:p>","DOI":"10.1002\/jgf2.242","type":"journal-article","created":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T05:09:54Z","timestamp":1554354594000},"page":"118-121","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Successful treatment of intractable menstrual migraine with the traditional herbal medicine tokishakuyakusan"],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6728-4966","authenticated-orcid":false,"given":"Tetsuya","family":"Akaishi","sequence":"first","affiliation":[{"name":"Department of Education and Support for Regional Medicine Tohoku University Hospital Sendai Japan"},{"name":"Department of Neurology Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Takayama","sequence":"additional","affiliation":[{"name":"Department of Education and Support for Regional Medicine Tohoku University Hospital Sendai Japan"},{"name":"Department of Kampo Medicine Tohoku University Hospital Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Ohsawa","sequence":"additional","affiliation":[{"name":"Department of Education and Support for Regional Medicine Tohoku University Hospital Sendai Japan"},{"name":"Department of Kampo Medicine Tohoku University Hospital Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Kikuchi","sequence":"additional","affiliation":[{"name":"Department of Education and Support for Regional Medicine Tohoku University Hospital Sendai Japan"},{"name":"Department of Kampo Medicine Tohoku University Hospital Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryutaro","family":"Arita","sequence":"additional","affiliation":[{"name":"Department of Education and Support for Regional Medicine Tohoku University Hospital Sendai Japan"},{"name":"Department of Kampo Medicine Tohoku University Hospital Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Department of Neurology Tohoku Medical and Pharmaceutical University Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of Neurology Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Education and Support for Regional Medicine Tohoku University Hospital Sendai Japan"},{"name":"Department of Kampo Medicine Tohoku University Hospital Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-199706000-00003"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2014.01.002"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X88000248"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1358\/mf.2000.22.10.802288"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/593560"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-0102(92)90020-D"},{"key":"e_1_2_5_9_1","first-page":"????","article-title":"Dysmenorrhoea","volume":"2007","author":"Proctor ML","year":"2007","journal-title":"BMJ Clin Evid"}],"container-title":["Journal of General and Family Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjgf2.242","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgf2.242","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jgf2.242","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgf2.242","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T17:14:29Z","timestamp":1694366069000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgf2.242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,3]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1002\/jgf2.242"],"URL":"https:\/\/doi.org\/10.1002\/jgf2.242","archive":["Portico"],"relation":{},"ISSN":["2189-7948","2189-7948"],"issn-type":[{"value":"2189-7948","type":"print"},{"value":"2189-7948","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,3]]},"assertion":[{"value":"2018-12-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}