{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T12:42:10Z","timestamp":1766580130243,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T00:00:00Z","timestamp":1583280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gen and Family Med"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The relationship between the risk of right heart failure in primary acute pulmonary embolism after embolization and the residual thrombus sites in the pelvis and lower limbs is not clear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This single\u2010center retrospective observational study examined the results of contrast\u2010enhanced computed tomography and venous ultrasonography of patients with primary acute PE and DVT. We assessed the association between the occurrence of right heart failure and age; gender; pulmonary thrombosis distribution; most proximal site of deep vein thrombosis in the soleal vein, inferior vena cava (IVC), or common iliac vein (CIV); DVT distribution; and malignancy using univariate and multivariate logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, 77 of 165 patients were male (mean age: 65.1\u00a0\u00b1\u00a013.7\u00a0years). Right heart failure occurred in 53 patients (32.1%). Multivariate analysis revealed that the odds ratio (OR) for right heart failure was significantly lower in patients with the most proximal site of DVT in the IVC\/CIV (OR\u00a0=\u00a00.07, 95% confidence interval [CI] 0.01\u20100.62, <jats:italic>P<\/jats:italic> = .017), while it was significantly higher in females (OR\u00a0=\u00a02.51, 95% CI 1.05\u20106.01, <jats:italic>P<\/jats:italic> = .039), and in patients who exhibited the presence of bilateral venous thrombosis (OR\u00a0=\u00a03.89, 95% CI 1.60\u20109.48, <jats:italic>P<\/jats:italic> = .003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A significant factor involved in PE without right heart failure was the most proximal site of DVT in the IVC\/CIV, and significant risk factors associated with PE with right heart failure were more prevalent in females and in patients who exhibited the presence of bilateral venous thrombosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgf2.305","type":"journal-article","created":{"date-parts":[[2020,3,5]],"date-time":"2020-03-05T01:48:05Z","timestamp":1583372885000},"page":"63-70","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A retrospective observational study investigating the factors associated with right heart failure in patients with primary acute pulmonary embolism and deep vein thrombosis"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1265-4007","authenticated-orcid":false,"given":"Satoshi","family":"Kobayashi","sequence":"first","affiliation":[{"name":"Department of Radiology Saitama Rehabilitation Center Ageo Japan"},{"name":"Department of Radiology Saitama Cardiovascular Respiratory Center Kumagaya Japan"},{"name":"Graduate School of Health Science Suzuka University of Medical Science Suzuka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Muto","sequence":"additional","affiliation":[{"name":"Division of Cardiology Saitama Cardiovascular Respiratory Center Kumagaya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Yabe","sequence":"additional","affiliation":[{"name":"Department of Radiology Saitama Rehabilitation Center Ageo Japan"},{"name":"Division of Health Sciences Graduate School of Medical Sciences Kanazawa University Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Imao","sequence":"additional","affiliation":[{"name":"Graduate School of Health Science Suzuka University of Medical Science Suzuka Japan"},{"name":"School of Radiological Sciences Faculty of Health Science Gunma Paz University Takasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukinori","family":"Okada","sequence":"additional","affiliation":[{"name":"Graduate School of Health Science Suzuka University of Medical Science Suzuka Japan"},{"name":"Department of Radiology St. Marianna University School of Medicine Kawasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.116.4.903"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.3.877"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-4-431-66893-0_4"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10396-007-0160-0"},{"key":"e_1_2_8_6_1","first-page":"1","article-title":"Guidelines for the diagnosis, treatment and prevention of pulmonary thromboembolism and deep vein thrombosis (JCS 2017)","author":"JCS Joint Working Group","year":"2018","journal-title":"Circ J"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.12110802"},{"key":"e_1_2_8_8_1","unstructured":"AmitaiY RogowskiO BendetU.Which method to measure RV\/LV diameter ratio is the best predictor of mortality in patients with acute PE? 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