{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T08:49:10Z","timestamp":1791449350502,"version":"4.3.3"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gen and Family Med"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Crohn's disease can present with various extraintestinal symptoms; however, laryngeal involvement, particularly epiglottic ulcers, is rare. A 52\u2010year\u2010old man presented with a sore throat. Laryngeal endoscopy revealed an epiglottic ulcer. He had no gastrointestinal symptoms. Further evaluation revealed a bamboo joint\u2010like appearance in the stomach and aphthous ulcers in the terminal ileum; thus, Crohn's disease was diagnosed. Treatment with prednisolone and mesalazine resulted in the resolution of symptoms without relapse. This case highlights that Crohn's disease can cause isolated epiglottic ulcers even in the absence of gastrointestinal symptoms and should be considered in the differential diagnosis of refractory throat ulcers.<\/jats:p>","DOI":"10.1002\/jgf2.70089","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T03:06:44Z","timestamp":1765595204000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epiglottic Ulceration as an Initial Manifestation of Crohn's Disease"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7267-5368","authenticated-orcid":false,"given":"Niina","family":"Yamashita","sequence":"first","affiliation":[{"name":"Department of General Internal Medicine Kobe City Medical Center General Hospital  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8636-2488","authenticated-orcid":false,"given":"Yoshiki","family":"Morihisa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Kobe City Medical Center General Hospital  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7619-0646","authenticated-orcid":false,"given":"Hiroaki","family":"Nishioka","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine Kobe City Medical Center General Hospital  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2017.04.010"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(02)00098-X"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100127549"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940311200108"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgf2.356"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.0422-22"},{"key":"e_1_2_11_8_1","volume-title":"Evidence\u2010Based Clinical Practice Guidelines for Inflammatory Bowel Disease (IBD)","author":"The Japanese Society of Gastroenterology","year":"2020"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(97)70100-7"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000002324"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1103481"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i20.3118"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000533479"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-4679(00)00258-4"}],"container-title":["Journal of General and Family Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgf2.70089","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jgf2.70089","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgf2.70089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:50:25Z","timestamp":1791445825000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgf2.70089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,12]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/jgf2.70089"],"URL":"https:\/\/doi.org\/10.1002\/jgf2.70089","archive":["Portico"],"relation":{},"ISSN":["2189-7948","2189-7948"],"issn-type":[{"value":"2189-7948","type":"print"},{"value":"2189-7948","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,12]]},"assertion":[{"value":"2025-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70089"}}