{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:59:12Z","timestamp":1790405952345,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gen and Family Med"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The prognostic significance of pharyngeal residue during routine swallowing assessment remains unclear in older adults at regional hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a single\u2010center retrospective cohort study of 107 consecutive patients (median age 87\u2009years) undergoing swallowing assessment at a regional hospital in Japan (January 2021\u2013December 2024; follow\u2010up until June 2025). The primary outcome was all\u2010cause mortality, and the secondary outcome was aspiration events. Time\u2010to\u2010event analyses used Kaplan\u2013Meier methods, multivariable Cox proportional hazards models, and Fine\u2013Gray subdistribution hazard models to account for the competing risk of death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During a median follow\u2010up of 72\u2009days (IQR 36\u2013156), 72 deaths and 63 aspiration events occurred. Pharyngeal residue was independently associated with aspiration events (HR 3.26; 95% CI 1.70\u20136.26;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and all\u2010cause mortality (HR 2.65; 95% CI 1.38\u20135.10;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). These findings were consistent in sensitivity analyses excluding antipsychotic use and in Fine\u2013Gray competing risks analysis (SHR 2.76; 95% CI 1.51\u20135.04;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Dementia was also independently associated with mortality (HR 1.83; 95% CI 1.02\u20133.29;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.044).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pharyngeal residue was independently associated with all\u2010cause mortality and aspiration events, supporting its utility as a simple prognostic marker for risk stratification in older adults with suspected dysphagia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jgf2.70148","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T04:30:08Z","timestamp":1787977808000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pharyngeal Residue Is Independently Associated With Mortality and Aspiration Events in Patients Undergoing Swallowing Assessment: A Retrospective Cohort Study"],"prefix":"10.1002","volume":"27","author":[{"given":"Yuki","family":"Chiko","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Fukuyama Minami Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizuma","family":"Omote","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Fukuyama Minami Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ei","family":"Miyasaka","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Fukuyama Minami Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122247"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.1.328"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12924"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26419"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-015-9631-4"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.178.2.1780393"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.5535\/arm.20180"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29770"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12124087"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-019-10036-7"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2013.54.5.1137"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-014-9578-x"}],"container-title":["Journal of General and Family Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgf2.70148","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jgf2.70148","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgf2.70148","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:22:50Z","timestamp":1790403770000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgf2.70148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,28]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/jgf2.70148"],"URL":"https:\/\/doi.org\/10.1002\/jgf2.70148","archive":["Portico"],"relation":{},"ISSN":["2189-7948","2189-7948"],"issn-type":[{"value":"2189-7948","type":"print"},{"value":"2189-7948","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,28]]},"assertion":[{"value":"2026-04-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70148"}}