{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T04:22:07Z","timestamp":1695529327472},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T00:00:00Z","timestamp":1493683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Gen and Family Med"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 74\u2010year\u2010old man with silicosis was admitted to the hospital because of prolonged fever. After referral to internal medicine for persistent fever and renal dysfunction, workup revealed antineutrophil cytoplasmic antibodies (<jats:styled-content style=\"fixed-case\">ANCA<\/jats:styled-content>) positivity. He was diagnosed with microscopic polyangiitis (<jats:styled-content style=\"fixed-case\">MPA<\/jats:styled-content>). After treatment with immunosuppressive therapy, his condition improved. Herein, we discuss silica exposure and the risk of <jats:styled-content style=\"fixed-case\">ANCA<\/jats:styled-content>\u2010associated vasculitis (<jats:styled-content style=\"fixed-case\">AAV<\/jats:styled-content>), particularly in terms of work\u2010related diseases. Silica exposure is a notorious risk factor for developing <jats:styled-content style=\"fixed-case\">AAV<\/jats:styled-content>, which is potentially lethal when not identified. When we see a silicosis patient with new\u2010onset prolonged fever and generalized fatigue, <jats:styled-content style=\"fixed-case\">AAV<\/jats:styled-content> should be taken into consideration. This case report provides beneficial information to reliably assess patients at high risk of developing <jats:styled-content style=\"fixed-case\">AAV<\/jats:styled-content> in primary care settings.<\/jats:p>","DOI":"10.1002\/jgf2.77","type":"journal-article","created":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T16:24:51Z","timestamp":1493742291000},"page":"288-290","source":"Crossref","is-referenced-by-count":4,"title":["Silicosis, then microscopic polyangiitis\u2014antineutrophil cytoplasmic antibodies\u2010associated vasculitis may be work\u2010related disease in patients with silicosis"],"prefix":"10.1002","volume":"18","author":[{"given":"Yoshito","family":"Nishimura","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Ako Central Hospital  Hyogo Japan"},{"name":"Department of General Medicine Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Tsuda","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ako Central Hospital  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Nishina","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ako Central Hospital  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiyoshi","family":"Omoto","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ako Central Hospital  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahito","family":"Misawa","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ako Central Hospital  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Yabe","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ako Central Hospital  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Nagao","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Ako Central Hospital  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2010.04.003"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.05.005"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2009.10.008"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.6400"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03501006"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kes230"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12199-014-0403-9"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(00)70260-5"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resinv.2012.10.002"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20327"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02828275"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.06.016"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2011.12.009"},{"key":"e_1_2_5_15_1","unstructured":"Japan Organization of Occupational Health and Safety.The research on pneumoconiosis. 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