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Although the disorder is a reversible pathological condition, in rare cases, it can cause serious sequelae or could even be fatal. Therefore, medications should be administered carefully, particularly in patients who require long\u2010term administration of large doses or those with liver dysfunction.<\/jats:p>","DOI":"10.1002\/jgf2.91","type":"journal-article","created":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T07:56:35Z","timestamp":1498031795000},"page":"436-438","source":"Crossref","is-referenced-by-count":6,"title":["Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7160-9380","authenticated-orcid":false,"given":"Yuki","family":"Onuma","sequence":"first","affiliation":[{"name":"Division of General Internal Medicine Department of Medicine Tokai University Oiso\u00a0Hospital  Isehara Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Oki","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine 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