{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T09:33:05Z","timestamp":1771493585407,"version":"3.50.1"},"reference-count":49,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T00:00:00Z","timestamp":1590710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Endoscopy\u2010based Kyoto classification predicts the risk of<jats:italic>Helicobacter pylori<\/jats:italic>infection and gastric cancer; however, the change in score following<jats:italic>H. pylori<\/jats:italic>eradication remains unknown. We retrospectively compared the Kyoto score before and after<jats:italic>H. pylori<\/jats:italic>eradication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>H. pylori\u2010<\/jats:italic>positive patients who underwent baseline esophagogastroduodenoscopy (EGD), successful<jats:italic>H. pylori<\/jats:italic>eradication, and surveillance EGD were enrolled. The Kyoto score is a sum of scores for atrophy (Kimura\u2010Takemoto atrophic\u2010border classification none or C1: 0, C\u2010II or C\u2010III: 1, O\u2010I to O\u2010III: 2), intestinal metaplasia (none: 0, antrum: 1, corpus and antrum: 2), enlarged folds (absence: 0, presence: 1), nodularity (absence: 0, presence: 1), and diffuse redness (none: 0, mild: 1, severe: 2) and ranges from 0 to 8.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighty\u2010three patients (mean age: 54.9\u2009years; 65.1% women) were enrolled. The mean duration from successful eradication to surveillance EGD was 256\u2009days. The Kyoto score significantly decreased from 3.90 to 2.78 following<jats:italic>H. pylori<\/jats:italic>eradication (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Scores for endoscopic atrophy (from 1.43 to 1.46,<jats:italic>P<\/jats:italic>= 0.638) and endoscopic intestinal metaplasia (from 0.53 to 0.47,<jats:italic>P<\/jats:italic>= 0.543) did not change; however, there was significant improvement in the scores for enlarged folds (from 0.14 to 0.00,<jats:italic>P<\/jats:italic>= 0.002), nodularity (from 0.18 to 0.04,<jats:italic>P<\/jats:italic>= 0.002), and diffuse redness (from 1.61 to 0.82,<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The Kyoto classification score decreased following<jats:italic>H. pylori<\/jats:italic>eradication. A decrease in the scores for enlarged folds, nodularity, and diffuse redness contributed to the decrease in Kyoto score.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgh3.12360","type":"journal-article","created":{"date-parts":[[2020,5,30]],"date-time":"2020-05-30T06:15:38Z","timestamp":1590819338000},"page":"909-914","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["<i>Helicobacter pylori<\/i>eradication improved the Kyoto classification score on endoscopy"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6953-6079","authenticated-orcid":false,"given":"Osamu","family":"Toyoshima","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Toyoshima Endoscopy Clinic Tokyo Japan"},{"name":"Department of Gastroenterology, Graduate School of Medicine The University of Tokyo Tokyo 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