{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T22:20:14Z","timestamp":1773699614434,"version":"3.50.1"},"reference-count":59,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T00:00:00Z","timestamp":1601856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Inflammatory bowel disease (IBD) and sarcoidosis, primarily considered distinct entities, share commonalties in pathophysiology and clinical manifestations. This study aimed to examine the in\u2010hospital outcomes of patients with concurrent IBD and sarcoidosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The National Inpatient Sample was used to identify hospitalized adult patients with IBD and sarcoidosis from 2010 to 2014. Primary outcomes were in\u2010hospital mortality, rates of septic shock, acute renal failure, respiratory failure, length of stay, and total hospitalization charges. Secondary outcomes were IBD\u2010specific complications and surgery interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 3995 patients with IBD and coexisting sarcoidosis (IBD\/sarcoidosis), of which 2500 patients had Crohn's disease with coexisting sarcoidosis (Crohn's disease [CD]\/sarcoidosis) and 1495 patients had ulcerative colitis with coexisting sarcoidosis (ulcerative colitis [UC]\/sarcoidosis), were included. Patients with IBD\/sarcoidosis had a lower risk of penetrating disease (adjusted odds ratio [aOR] 0.3, 95% confidence interval [CI] 0.16\u20130.55, <jats:italic>P<\/jats:italic> &lt;\u20090.0001) and colectomy (aOR 0.48, 95% CI 0.27\u20130.84, <jats:italic>P<\/jats:italic> &lt;\u20090.05). Subgroup analysis demonstrated lower rates of colectomy when comparing CD\/sarcoidosis (<jats:italic>P<\/jats:italic> &lt;\u20090.05) and UC\/sarcoidosis (<jats:italic>P<\/jats:italic> =\u20090.0003) <jats:italic>versus<\/jats:italic> CD or UC alone. There was no difference in mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>IBD\/sarcoidosis is associated with lower risks of penetrating disease and colectomy when compared to patients with IBD alone.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgh3.12423","type":"journal-article","created":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T13:22:18Z","timestamp":1601904138000},"page":"1199-1206","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sarcoidosis is associated with lower risks of penetrating disease and colectomy in hospitalized patients with inflammatory bowel disease"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5114-0183","authenticated-orcid":false,"given":"Yi","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Medicine Rutgers New Jersey Medical School  Newark New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel S","family":"Rim","sequence":"additional","affiliation":[{"name":"Department of Medicine Rutgers New Jersey Medical School  Newark New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Rodgers","sequence":"additional","affiliation":[{"name":"Department of Medicine Rutgers New Jersey Medical School  Newark New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sushil","family":"Ahlawat","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Rutgers New Jersey Medical School  Newark New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2340"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200606-136MS"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11582"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200402-249OC"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2006.11.007"},{"key":"e_1_2_6_7_1","first-page":"255","article-title":"Pulmonary function tests, high\u2010resolution computed tomography findings and inflammatory bowel disease","volume":"69","author":"Tunc B","year":"2006","journal-title":"Acta Gastroenterol. 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