{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T12:32:14Z","timestamp":1784896334052,"version":"3.55.0"},"reference-count":4,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Closure of mucosal defects after duodenal endoscopic submucosal dissection (ESD) is important to prevent postoperative adverse events. Previously, we devised an underwater reopenable\u2010clip closure method for effective closure of mucosal defects under endoscopic guidance within the field of view. Recently, the usefulness of a method using a clip with a line passing through an accessory channel to close a mucosal defect has been reported. We also described a reopenable\u2010clip over the line method (ROLM) to completely close margin and the muscular layers of mucosal defects using a clip line.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>Our patient was a 70\u2010year\u2010old woman with a 40\u2010mm duodenal tumor in the descending portion of the duodenum. The lesion was completely resected using ESD . In the result, the mucosal defect size was approximately 50 mm, representing about 3\/4 of the duodenal circumference. A clip\u2010line closure was performed using ROLM to close the mucosal defect's margins completely. An additional clip was applied to close the mucosal defect after ESD completely. Subsequently, the line was fixed with a modified locking\u2010clip technique, closed, and cut with endoscopic scissors. The patient was discharged without any adverse events 9 days after the duodenal ESD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Mucosal defect closure after duodenal ESD using ROLM is a novel method that can reliably close mucosal defects.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgh3.12577","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T14:43:48Z","timestamp":1622126628000},"page":"831-833","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Mucosal defect closure after duodenal endoscopic submucosal dissection using the reopenable\u2010clip over the line method"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1243-8846","authenticated-orcid":false,"given":"Tatsuma","family":"Nomura","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Mie Prefectural Shima Hospital  Shima Japan"},{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Sugimoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Tsuda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryutaro","family":"Matsushima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Oyamada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Kamei","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vgie.2020.06.015"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.12682"},{"key":"e_1_2_2_4_1","article-title":"Clip\u2010line closure using reopenable\u2010clip over the line method for large mucosal defect after gastric ESD","author":"Nomura T","year":"2021","journal-title":"Endoscopy"},{"key":"e_1_2_2_5_1","article-title":"Large colorectal mucosal defect closure post\u2010endoscopic submucosal dissection using the reopenable clip over line method and modified locking\u2010clip technique","author":"Nomura T","year":"2021","journal-title":"Endoscopy"}],"container-title":["JGH Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgh3.12577","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jgh3.12577","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgh3.12577","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T01:38:01Z","timestamp":1693359481000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgh3.12577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,27]]},"references-count":4,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1002\/jgh3.12577"],"URL":"https:\/\/doi.org\/10.1002\/jgh3.12577","archive":["Portico"],"relation":{},"ISSN":["2397-9070","2397-9070"],"issn-type":[{"value":"2397-9070","type":"print"},{"value":"2397-9070","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,27]]},"assertion":[{"value":"2021-03-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}