{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:21:32Z","timestamp":1747149692574,"version":"3.40.5"},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T00:00:00Z","timestamp":1624320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pyogenic liver abscess (PLA) is an uncommon yet potentially fatal disease. The disease most commonly arises from biliary infection but may also result from hematogenous seeding and portal spread secondary to bowel contamination, direct seeding, or penetrating trauma. The diagnosis is suspected when there is a hepatic lesion on imaging. Confirmation of diagnosis requires purulent aspirate or bacterial growth on Gram stain\/culture of the abscess or blood. The mainstay of treatment is antimicrobials in conjunction with either percutaneous abscess drainage or aspiration. Surgical drainage is reserved for cases of ruptured abscess, peritonitis, or in the presence of an underlying surgical cause. PLA typically presents with fever and abdominal symptoms. We report a case of an unusual manifestation of PLA, presenting as hiccups, which led to a significant delay in the diagnosis and treatment.<\/jats:p>","DOI":"10.1002\/jgh3.12591","type":"journal-article","created":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T10:45:26Z","timestamp":1624358726000},"page":"837-838","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["When hiccups mean something more than just a nuisance: A rare presentation of pyogenic liver abscess"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5219-6277","authenticated-orcid":false,"given":"Muaaz","family":"Masood","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Medical College of Georgia at Augusta University  Augusta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pearl","family":"Uy","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Medical College of Georgia at Augusta University  Augusta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0441-3211","authenticated-orcid":false,"given":"John E","family":"Yap","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Medical College of Georgia at Augusta University  Augusta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,22]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"1067","article-title":"Pyogenic liver abscess: changes of organisms and consequences for diagnosis and therapy","volume":"142","author":"Mischnik A","year":"2017","journal-title":"Dtsch Med Wochenschr"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00459-8"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-017-2256-9"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-018-0856-0"},{"key":"e_1_2_4_6_1","first-page":"Cd008768","article-title":"Interventions for treating persistent and intractable hiccups in adults","volume":"2013","author":"Moretto EN","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_4_7_1","first-page":"92","article-title":"Hiccups: an uncommon presentation of pyogenic liver abscess","volume":"83","author":"Wu ZF","year":"2020","journal-title":"Acta Gastroenterol. Belg."},{"key":"e_1_2_4_8_1","first-page":"203","article-title":"Liver abscess presenting with persistent hiccups and right shoulder pain","volume":"113","author":"Lee C\u2010C","year":"2019","journal-title":"QJM Int J Med."},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199603000-00006"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1986.01400050072009"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.09.058"}],"container-title":["JGH Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgh3.12591","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jgh3.12591","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgh3.12591","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T01:37:56Z","timestamp":1693359476000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgh3.12591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,22]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1002\/jgh3.12591"],"URL":"https:\/\/doi.org\/10.1002\/jgh3.12591","archive":["Portico"],"relation":{},"ISSN":["2397-9070","2397-9070"],"issn-type":[{"type":"print","value":"2397-9070"},{"type":"electronic","value":"2397-9070"}],"subject":[],"published":{"date-parts":[[2021,6,22]]},"assertion":[{"value":"2021-05-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}