{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T11:21:38Z","timestamp":1777029698213,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T00:00:00Z","timestamp":1629936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>We prospectively compared the clinical outcomes of radical and conservative surgical procedures for primary liver hydatid cysts, additionally radical surgical procedures with and without the two\u2010month administration of albendazole after the operation were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Overall, 90 patients undergoing open surgical treatment for liver hydatid cysts were divided into three surgical groups: first group, patients who underwent radical surgery (pericystectomy) followed by albendazole treatment for 2\u00a0months following the operation group; second group, patients who underwent radical surgery(pericystectomy) without receiving albendazole after surgery group; third group, patients, who underwent conservative surgery (partial cystectomy) with albendazole treatment after surgery. The clinical outcomes and rate of recurrence were analyzed in follow\u2010up period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean surgery duration in the Radical groups was significantly longer in comparison to the Conservative surgery\u2009+\u2009Albendazole group. (212.0 and 202.5\u00a0min vs. 173.2\u2009min; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Blood loss in the Radical groups was significantly higher in comparison to the Conservative surgery\u2009+\u2009Albendazole group (218.3 and 174.6\u00a0ml vs. 67.2\u2009ml; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). However, postoperative complication rate in the Radical group was significantly lower in comparison to Conservative surgery\u2009+\u2009Albendazole group (13.3% [<jats:italic>n<\/jats:italic>\u00a0=\u00a04] and 6.7% [<jats:italic>n<\/jats:italic>\u00a0=\u00a02] vs. 36% [<jats:italic>n<\/jats:italic>\u00a0=\u00a011]; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The postoperative hospital stay in both Radical groups was significantly lower in comparison to the Conservative surgery\u2009+\u2009Albendazole group (7.9 and 7.4\u2009days vs. 11.3\u2009days; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In comparison to conservative surgery, radical surgery is a preferable treatment modality for patients with active liver hydatid cysts. Postoperative albendazole treatment is preferable, regardless of the type of surgical procedure.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgh3.12649","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T04:45:00Z","timestamp":1630039500000},"page":"1179-1182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Radical <i>versus<\/i> conservative surgical management for liver hydatid cysts: A single\u2010center prospective cohort study"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1887-7866","authenticated-orcid":false,"given":"Zhassulan","family":"Baimakhanov","sequence":"first","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shokan","family":"Kaniyev","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erbol","family":"Serikuly","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxat","family":"Doskhanov","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baglan","family":"Askeyev","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinara","family":"Baiguissova","sequence":"additional","affiliation":[{"name":"Department of Radiology Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aidar","family":"Skakbayev","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chingiz","family":"Sadykov","sequence":"additional","affiliation":[{"name":"Department of Radiology Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raikhan","family":"Barlybay","sequence":"additional","affiliation":[{"name":"Department of Radiology Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manas","family":"Seisembayev","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Syzganov's National Scientific Center of Surgery  Almaty Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bolatbek","family":"Baimakhanov","sequence":"additional","affiliation":[{"name":"Department of HPB Surgery and Liver Transplantation Syzganov's National Scientific Center of Surgery  Almaty 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