{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:16:06Z","timestamp":1789784166568,"version":"4.0.1"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,29]],"date-time":"2021-12-29T00:00:00Z","timestamp":1640736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Meckel's diverticulum (MD) is a common congenital abnormality of the gastrointestinal (GI) tract. Although a few patients with MD present symptoms, preoperative diagnosis of MD is a clinical challenge because of its endoscopic inaccessibility. The aim of the present study was to investigate patients with MD diagnosed by double\u2010balloon enteroscopy (DBE) in Taiwan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective study in a tertiary referral center in middle Taiwan. The clinical characteristics, endoscopic features, histopathological findings, treatment methods, and outcomes of patients with MD diagnosed by DBE were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 14 male patients with MD diagnosed by DBE were enrolled. The mean age of all patients was 32.3\u2009years. GI bleeding (78.6%) accounted for the major indication of DBE, followed by abdominal pain and Crohn's disease follow\u2010up. The mean distance between the ileocecal valve and MD was 68.9\u00a0cm. The average length of 12 patients with surgically resected MD was 5.2\u00a0cm. The diagnostic yields of the other modalities excepting DBE are as follows: capsule endoscopy, 50%; Meckel's scan, 11.1%; computed tomography, 16.7%; small bowel series, 0%; and angiography, 33.3%. MD presented as a large ostium in 13 patients (92.9%), a small ostium in 1 patient (7.1%), and bleeding signs in 10 patients (71.4%). Twelve patients (85.7%) underwent surgical treatment and 2 patients (14.3%) received conservative treatment. Heterotopic gastric tissue was identified in 4 patients (28.6%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study showed that DBE is a more powerful modality in detecting MD than the other conventional modalities in Taiwan.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgh3.12697","type":"journal-article","created":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T07:41:02Z","timestamp":1640850062000},"page":"63-68","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Meckel's diverticulum diagnosed by double\u2010balloon enteroscopy: A single\u2010center retrospective study in Taiwan"],"prefix":"10.1002","volume":"6","author":[{"given":"Kai\u2010Chih","family":"Chang","sequence":"first","affiliation":[{"name":"Center for Digestive Medicine, Department of Internal Medicine China Medical University Hospital  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Hsi","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine Asia University Hospital  Taichung Taiwan"},{"name":"Taiwan Association for the Study of Small Intestinal Diseases (TASSID)  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4674-6487","authenticated-orcid":false,"given":"Jen\u2010Wei","family":"Chou","sequence":"additional","affiliation":[{"name":"Center for Digestive Medicine, Department of Internal Medicine China Medical University Hospital  Taichung Taiwan"},{"name":"Taiwan Association for the Study of Small Intestinal Diseases (TASSID)  Taoyuan Taiwan"},{"name":"School of Medicine China Medical University  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Hua","family":"Wu","sequence":"additional","affiliation":[{"name":"Center for Digestive Medicine, Department of Internal Medicine China Medical University Hospital  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po\u2010Ju","family":"Huang","sequence":"additional","affiliation":[{"name":"Center for Digestive Medicine, Department of Internal Medicine China Medical University Hospital  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken\u2010Sheng","family":"Cheng","sequence":"additional","affiliation":[{"name":"Center for Digestive Medicine, Department of Internal Medicine China Medical University Hospital  Taichung Taiwan"},{"name":"School of Medicine China Medical University  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,29]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"421","article-title":"Ueber die divertikel am darmkanal","volume":"9","author":"Meckel JF","year":"1809","journal-title":"Arch. 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