{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:06:28Z","timestamp":1760781988613,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Laparoscopic cholecystectomy (LC) with intraoperative cholangiography (IOC) is a commonly performed surgical procedure in most hospitals. Anecdotal evidence suggests that when the pancreatic duct (PD) inadvertently fills during IOC, there may be an increased risk of postoperative pancreatitis (POP). However, there is a paucity of information in the literature about both the incidence of pancreatitis post LC and the incidence of PD filling on IOC and any potential relationship between the two.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review was performed of all LC performed in our institution over a 10\u2010year period. IOC images were reviewed and clinical data collated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 1243 procedures identified, 952 had IOC images available for review and were included in the study. The incidence of POP was 0.7%. The incidence of PD filling was 13.4%. Patient's age, sex, urgency of surgery, preoperative liver function tests (LFTs), history of pancreatitis, contrast leakage, and preoperative endoscopic retrograde cholangiopancreatography (ERCP) were not statistically related to the incidence of POP. Of those with PD filling, 2% had POP <jats:italic>versus<\/jats:italic> 0.5% who had no PD filling. This trended toward significance on univariate analysis (<jats:italic>P<\/jats:italic>\u2009=\u20090.05). However, on logistic regression, POP was the only significant independent risk factor (<jats:italic>P<\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidence of pancreatitis post LC and IOC is low. PD filling is associated with increased incidence of pancreatitis in this scenario and it is crucial for clinicians to be aware of this potential risk. This retrospective study was based on the review of saved images, and therefore PD filling might have been underestimated. Prospective studies would be useful to ascertain any definitive clinical association.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgh3.12954","type":"journal-article","created":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T08:54:05Z","timestamp":1690880045000},"page":"584-587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pancreatic duct filling during cholecystectomy intraoperative cholangiogram and incidence of postoperative pancreatitis"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4872-772X","authenticated-orcid":false,"given":"M Masood","family":"Sidiqi","sequence":"first","affiliation":[{"name":"Department of General Surgery Armadale Kelmscott District Memorial Hospital  Perth Western Australia Australia"},{"name":"University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina","family":"Guirgis","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale Kelmscott District Memorial Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Sala","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale Kelmscott District Memorial Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Ballal","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale Kelmscott District Memorial Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"103","article-title":"The importance of intraoperative cholangiography during laparoscopic cholecystectomy","volume":"4","author":"Polat FR","year":"2000","journal-title":"JSLS"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-003-0884-1"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ases.12181"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/003655202760230937"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198607000-00008"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01655510"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02290203"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800601205"},{"key":"e_1_2_6_10_1","first-page":"93","article-title":"Pancreatic\u2010duct reflux in patients with gallstone pancreatitis?","volume":"7","author":"Taylor TV","year":"1980","journal-title":"Lancet"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-008-0010-5"},{"key":"e_1_2_6_12_1","first-page":"182","article-title":"The etiology of acute hemorrhagic pancreatitis","volume":"12","author":"Opie EL","year":"1901","journal-title":"Bull. 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