{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:22:24Z","timestamp":1747149744454,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T00:00:00Z","timestamp":1695081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Hepatic steatosis (HS) is common worldwide, but there is little data on the prevalence of HS in Pacific Islanders (PIs) and Asians within the United States. Our aim was to compare prevalence of HS in obese 18\u201350\u2010year\u2010olds of Asian and PI ethnicity who underwent computerized tomography (CT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective analysis of all members of an integrated healthcare system who self\u2010identified as Asian or PI, were between the ages of 18 and 50\u2009years, had a body mass index (BMI)\u2009\u2265\u200930, and underwent a CT scan that included the liver during 2021, resulting in 748 subjects. Imaging was analyzed using a method sensitive and specific for moderate to severe HS. Additionally, multiple binary logistic regression was performed to explore the relationship between HS and HbA1c, BMI, and age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 748 patients, 311 (41.6%) had HS. We found no significant difference in the prevalence of HS between Asians and PIs (\u03c7<jats:sup>2<\/jats:sup><jats:sub>1<\/jats:sub>\u2009=\u20091.3, <jats:italic>P<\/jats:italic>\u2009=\u20090.25), between Asian and PI men (\u03c7<jats:sup>2<\/jats:sup><jats:sub>1<\/jats:sub>\u2009=\u20092.8, <jats:italic>P<\/jats:italic>\u2009=\u20090.096), or between Asian and PI women (\u03c7<jats:sup>2<\/jats:sup><jats:sub>1<\/jats:sub>\u2009=\u20090.053, <jats:italic>P<\/jats:italic>\u2009=\u20090.82). Higher odds of HS was associated with increasing BMI (OR\u2009=\u20091.08; 95% CI: 1.06\u20131.11; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and HbA1c (OR\u2009=\u20091.15; 95% CI: 1.04\u20131.26; <jats:italic>P<\/jats:italic>\u2009=\u20090.00489), but HS was not associated with age in this age range (OR\u2009=\u20090.993; 95% CI: 0.973\u20131.01; <jats:italic>P<\/jats:italic>\u2009=\u20090.46).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Moderate to severe HS is very common in obese Asian and PI adults, and occurs at similar rates in these ethnicities. Abdominal CT imaging presents an opportunity to diagnose HS and provides relevant information to patients and healthcare providers.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgh3.12968","type":"journal-article","created":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T06:55:46Z","timestamp":1695192946000},"page":"698-701","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Moderate to severe hepatic steatosis on computerized tomography imaging: Prevalence in obese Pacific Islanders and Asians"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8544-8810","authenticated-orcid":false,"given":"Bradley James Ikaika","family":"Thomas","sequence":"first","affiliation":[{"name":"John A. Burns School of Medicine University of Hawai'i at Manoa  Honolulu Hawai USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8362-9597","authenticated-orcid":false,"given":"Melia Nicole","family":"Takakusagi","sequence":"additional","affiliation":[{"name":"John A. Burns School of Medicine University of Hawai'i at Manoa  Honolulu Hawai USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruixue","family":"Zhang","sequence":"additional","affiliation":[{"name":"John A. Burns School of Medicine University of Hawai'i at Manoa  Honolulu Hawai USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyo\u2010Chun","family":"Yoon","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging, Hawaii Permanente Medical Group  Honolulu Hawaii USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28431"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.10.033"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.02.034"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.06.0992"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.20.24415"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-1966"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.2590"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2012.02.022"},{"key":"e_1_2_5_10_1","first-page":"1","article-title":"Health conditions and behaviors of Native Hawaiian and Pacific Islander persons in the United States, 2014. National Center for Health Statistics","volume":"3","author":"Galinsky AM","year":"2017","journal-title":"Vital Health Stat."},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2017.10.002"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.7812\/TPP\/22.057"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28677"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1765"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eprac.2022.03.010"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/acem.14174"}],"container-title":["JGH Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgh3.12968","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T15:47:06Z","timestamp":1698680826000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgh3.12968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,19]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/jgh3.12968"],"URL":"https:\/\/doi.org\/10.1002\/jgh3.12968","archive":["Portico"],"relation":{},"ISSN":["2397-9070","2397-9070"],"issn-type":[{"type":"print","value":"2397-9070"},{"type":"electronic","value":"2397-9070"}],"subject":[],"published":{"date-parts":[[2023,9,19]]},"assertion":[{"value":"2023-04-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}