{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T10:42:28Z","timestamp":1780742548229,"version":"3.54.1"},"reference-count":13,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T00:00:00Z","timestamp":1695081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Inflammatory bowel diseases (IBD), including ulcerative colitis, are chronic autoimmune conditions characterized by inflammation of the digestive system. The exact cause of IBD is unknown, but they often start during adolescence or early adulthood with symptoms such as urgency, rectal bleeding, diarrhea, abdominal pain and tenesmus. Primary sclerosing cholangitis and autoimmune hepatitis are recognized as co\u2010occurring conditions associated with ulcerative colitis. However, the combination of ulcerative colitis, primary sclerosing cholangitis, liver cirrhosis, and celiac disease occurring concurrently has only been reported once before in a female patient. Here, we present the exceptional case of a Syrian adult male with all four of these conditions. This highlights the importance of screening for both celiac disease and cirrhosis in patients with ulcerative colitis and primary sclerosing cholangitis together, despite this combination of comorbidities is rare.<\/jats:p>","DOI":"10.1002\/jgh3.12971","type":"journal-article","created":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T09:54:42Z","timestamp":1695117282000},"page":"731-733","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of ulcerative colitis, celiac disease, primary sclerosing cholangitis and liver cirrhosis in a young male"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6128-0515","authenticated-orcid":false,"given":"Ahmad N.","family":"Alkhaledi","sequence":"first","affiliation":[{"name":"Department of Oncology, Faculty of Medicine Damascus University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isra","family":"Jadaan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Faculty of Medicine Damascus University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad Zaher","family":"Sharfo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine Damascus University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tala","family":"Faysal","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine Damascus University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2338-3601","authenticated-orcid":false,"given":"Yazane","family":"Abdallah","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine Damascus University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Alhaj Ali","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Faculty of Medicine Damascus University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2015.150"},{"key":"e_1_2_6_3_1","volume-title":"Sleisenger and Fordtran's Gastrointestinal and Liver Disease","author":"MD FMSFMJB","year":"2021"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2005.00291.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv213"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12794"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MIB.0000161308.65951.db"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2009.08.005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-109-9-713"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200207000-00014"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.meg.0000059152.68845.53"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i33.6137"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjy166"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-019-0702-3"}],"container-title":["JGH Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jgh3.12971","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T15:47:25Z","timestamp":1698680845000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgh3.12971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,19]]},"references-count":13,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/jgh3.12971"],"URL":"https:\/\/doi.org\/10.1002\/jgh3.12971","archive":["Portico"],"relation":{},"ISSN":["2397-9070","2397-9070"],"issn-type":[{"value":"2397-9070","type":"print"},{"value":"2397-9070","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,19]]},"assertion":[{"value":"2023-06-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}