{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T18:45:35Z","timestamp":1784141135933,"version":"3.55.0"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T00:00:00Z","timestamp":1715126400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p><jats:italic>Helicobacter pylori<\/jats:italic> represents the major pathogen in the pathophysiology of diverse gastrointestinal conditions. This study sought to determine the endoscopic aspect of the gastric mucosa in relation to <jats:italic>H. pylori<\/jats:italic> infection in Cameroon.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was conducted in three reference health facilities in Cameroon from October 2020 to October 2022. The study enrolled 494 consecutive volunteer dyspeptic patients attending to the gastroenterology department of the selected health facilities. A description of the aspect of gastric mucosa of all participants was performed during endoscopy examination, and biopsies were collected for <jats:italic>H. pylori<\/jats:italic> detection using rapid urease tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Gastritis, ulcerated lesions, duodenitis, esophagitis, normal mucosa aspect, bulbitis, and gastric neoplastic lesions were found in 40.1, 22.3, 10.9, 10.3, 9.7, 6.3, and 0.40% of biopsy samples, respectively. Erythematous\/exudative (45.9%) and enterogastric reflux (12.2%) were the main gastritis types recorded. <jats:italic>H. pylori<\/jats:italic> was present in 58.1, 46.3, 87.1, 66.7, and 61.8% in gastritis, duodenitis, bulbitis, esophagitis, and ulcerated lesions, respectively. A positive relationship was noticed between the presence of <jats:italic>H. pylori<\/jats:italic> and gastritis (1.037 [0.720\u20131.493]; <jats:italic>P<\/jats:italic>\u2009=\u20090.845), bulbitis (4.237 [1.602\u201311.235]; <jats:italic>P<\/jats:italic>\u2009=\u20090.004), esophagitis (1.515 [0.822\u20132.793]; <jats:italic>P<\/jats:italic>\u2009=\u20090.183), ulcerated lesions (1.233 [0.798\u20131.904]; <jats:italic>P<\/jats:italic>\u2009=\u20090.345), erythematous\/exudative gastritis (1.354 [0.768\u20132.389]; <jats:italic>P<\/jats:italic>\u2009=\u20090.295), and enterogastric reflux gastritis (1.159 [0.492\u20132.733]; <jats:italic>P<\/jats:italic>\u2009=\u20090.736).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Gastritis and erythematous\/exudative gastritis are the most frequent gastrointestinal pathophysiology conditions in dyspeptic patient in our milieu. <jats:italic>H. pylori<\/jats:italic> infection is responsible for 94.8% of the gastrointestinal pathophysiology conditions with bulbitis as the condition is significantly associated with this bacterium infection.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jgh3.13060","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T02:19:03Z","timestamp":1715221143000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Endoscopic mucosal phenotypes and endoscopic Sydney system gastritis assessment in relation to <i>Helicobacter pylori<\/i> infection and upper digestive clinical signs: A 2\u2010year study among patients with gastroduodenal disorders in Cameroon"],"prefix":"10.1002","volume":"8","author":[{"given":"Lionel Danny","family":"Tali Nguefak","sequence":"first","affiliation":[{"name":"Microbiology and Pharmacology Laboratory, Department of Biochemistry, Faculty of Science University of Dschang  Dschang 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Cath\u00e9drale  Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sartre Michele","family":"Tagni","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Centre M\u00e9dicale la Cath\u00e9drale  Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nzoume Nsope Mengang","family":"Jude\u2010Marcel","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Regional Hospital Bafoussam  Bafoussam Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dzoyem Jean","family":"Paul","sequence":"additional","affiliation":[{"name":"Microbiology and Pharmacology Laboratory, Department of Biochemistry, Faculty of Science University of Dschang  Dschang Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6447-1413","authenticated-orcid":false,"given":"Laure Brigitte","family":"Kouitcheu 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