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Although the prevalence of <jats:styled-content style=\"fixed-case\"><jats:italic>H. pylori<\/jats:italic><\/jats:styled-content> infection has decreased among adults, it is still very common. Approximately 90% of gastric adenocarcinomas are associated with <jats:styled-content style=\"fixed-case\"><jats:italic>H. pylori<\/jats:italic><\/jats:styled-content> infection. Despite the established link between <jats:styled-content style=\"fixed-case\"><jats:italic>H. pylori<\/jats:italic><\/jats:styled-content> infection and noncardiac gastric cancer, and the increasing incidence of gastric cancer in Kazakhstan, there are limited data on the prevalence of <jats:styled-content style=\"fixed-case\"><jats:italic>H. pylori<\/jats:italic><\/jats:styled-content> in the country. This may be due to the difficulty of detecting <jats:styled-content style=\"fixed-case\"><jats:italic>H. pylori<\/jats:italic><\/jats:styled-content> and the unavailability of diagnostic methods. This review presents the current data of diagnostic tests for the detection of <jats:styled-content style=\"fixed-case\"><jats:italic>H. pylori<\/jats:italic><\/jats:styled-content> in Kazakhstan with a focus on limitations and practical significance.<\/jats:p>","DOI":"10.1002\/jgh3.70101","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T11:50:40Z","timestamp":1737114640000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Review of Methods for Detection <i>Helicobacter pylori<\/i> in Kazakhstan"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9436-8778","authenticated-orcid":false,"given":"Lavrinenko","family":"Alyona","sequence":"first","affiliation":[{"name":"Laboratory of the Institute of Life Sciences NJSC Karaganda Medical University  Karaganda Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2458-2582","authenticated-orcid":false,"given":"Seisenbekova","family":"Aizhan","sequence":"additional","affiliation":[{"name":"Department of Internal Diseases Karaganda Medical University  Karaganda Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2322-304X","authenticated-orcid":false,"given":"Turemuratova","family":"Aidana","sequence":"additional","affiliation":[{"name":"Scientific Research Laboratory of the Institute of Life Sciences NJSC Karaganda Medical University  Karaganda Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0918-6836","authenticated-orcid":false,"given":"Shkreba","family":"Alexey","sequence":"additional","affiliation":[{"name":"University Clinic NJSC, Karaganda Medical University  Karaganda Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5992-0336","authenticated-orcid":false,"given":"Yukhnevich","family":"Yekaterina","sequence":"additional","affiliation":[{"name":"Karaganda Medical University  Karaganda Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-023-00431-8"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2022.215764"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i18.5461"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11051312"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756284821989177"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10163473"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms12010222"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2023.12.022"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s10038-021-00960-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12734"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-13-1215"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(23)00070-5"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.36488\/cmac.2018.1.14-23"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2023.09.047"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28999"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules20046068"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2022.23.6.1935"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2022.23.11.3779"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v29.i16.2452"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-016-7495-7"},{"issue":"3","key":"e_1_2_7_22_1","article-title":"Non\u2010Invasive Diagnostic Tests for \n                     Helicobacter pylori\n                   Infection","volume":"3","author":"Best L. 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