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Gastric NETs (G\u2010NETs) originate from endocrine progenitor cells in the basal layer of the mucosa, primarily in the setting of chronic atrophic gastritis, such as autoimmune gastritis. They generally exhibit low malignancy and a favorable prognosis. By contrast, gastric NECs (G\u2010NECs), a rare subtype of gastric cancers, arise from endocrine precursor cell clones that dedifferentiate in the deep portion of pre\u2010existing differentiated\u2010type adenocarcinomas. G\u2010NECs are characterized by rapid growth, frequent lymphovascular invasion, high metastatic potential, and aggressive biological behavior. Most G\u2010NEC cases are therefore diagnosed at advanced stages, often with lymph node or distant metastases, leading to a poorer prognosis than gastric adenocarcinomas. Furthermore, endoscopic diagnosis of G\u2010NECs remains challenging because of the low sensitivity of biopsy\u2010based techniques. While it is well established that G\u2010NETs and G\u2010NECs have distinct clinicopathological characteristics, information on their endoscopic features, particularly those observed with magnifying narrow\u2010band imaging, remains limited. This review aims to summarize the characteristic endoscopic findings of G\u2010NETs and G\u2010NECs in relation to their clinicopathological findings.<\/jats:p>","DOI":"10.1002\/jgh3.70272","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T08:16:57Z","timestamp":1758615417000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Differences in Endoscopic Features of Gastric Neuroendocrine Tumor and Neuroendocrine Carcinoma From a Clinicopathological Perspective"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6497-730X","authenticated-orcid":false,"given":"Katsunori","family":"Matsueda","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriya","family":"Uedo","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Kitamura","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology and Cytology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiji","family":"Kawano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoyuki","family":"Otsuka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,23]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"WHO Classification of Endocrine and Neuroendocrine Tumours","author":"WHO Classification of Tumours Editorial Board","year":"2022"},{"key":"e_1_2_8_3_1","volume-title":"WHO Classification of Digestive Tumours","author":"WHO Classification of Tumours Editorial Board","year":"2019"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-024-00508-y"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12022-022-09708-2"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2017.0589"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000486915"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-020-01046-8"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2016.1236397"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.13500"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-020-07581-y"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.2177"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255564"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000338295"},{"key":"e_1_2_8_15_1","first-page":"9","article-title":"Update on Autoimmune Polyendocrine Syndromes (APS)","volume":"74","author":"Betterle C.","year":"2003","journal-title":"Acta Bio\u2010Medica"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-2134"},{"key":"e_1_2_8_17_1","first-page":"22","article-title":"The Association Between Autoimmune Thyroiditis, Autoimmune Gastritis and Type 1 Diabetes","volume":"1","author":"Lam\u2010Tse W. 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