{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:14:38Z","timestamp":1769645678712,"version":"3.49.0"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T00:00:00Z","timestamp":1769299200000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Previous studies have shown an increased prevalence of eosinophilic gastrointestinal disease (EGID) in pediatric liver and heart transplant recipients. However, EGID after other solid organ and bone marrow transplantations has not been extensively evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The purpose of this study is to determine relationships between subsets of EGID with different solid organ and bone marrow transplants in pediatric patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a single\u2010center retrospective chart review of pediatric patients with transplant and EGID between 2007 and 2023. For comparison between transplant groups, ANOVA was used for statistical analysis of continuous variables, and Fisher's exact test was used for categorical variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 30 patients with EGID (eosinophilic esophagitis [EoE]\u2009=\u200921; eosinophilic gastritis [EoG]\u2009=\u20094; EoE\u2009+\u2009EoG\u2009=\u20093; EoE\u2009+\u2009eosinophilic colitis [EoC]\u2009=\u20091; eosinophilic duodenitis [EoD]\u2009=\u20091) and history of transplant (liver\u2009=\u200915; heart\u2009=\u20099; bone marrow\u2009=\u20093; multivisceral liver + small bowel + pancreas\u2009=\u20092; kidney\u2009=\u20091). When comparing the transplant groups, there was a significant difference in EoE\u2009+\u2009EoG incidence (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011), specifically, EoE\u2009+\u2009EoG was present in 2 (100%) multivisceral and in 1\/15 (7%) liver transplant patients. A statistically significant difference in the presence of gastroesophageal reflux (GER) and oral allergy syndrome between groups was noted (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.033). There was no significant difference in the symptoms leading to EGID work\u2010up: incidence; morphologic features; achievement of histologic remission; medications; or family history of atopy between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This retrospective biopsy\u2010confirmed cohort demonstrates that EGID subtype varies by transplant type, with higher rates of EoE\u2009+\u2009EoG in multivisceral recipients. Findings are exploratory and hypothesis\u2010generating; larger multicenter studies including more non\u2010liver and non\u2010heart transplant patients are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jgh3.70344","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T05:01:18Z","timestamp":1769403678000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Eosinophilic Gastrointestinal Disease After Pediatric Organ and Bone Marrow Transplantation"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1038-5272","authenticated-orcid":false,"given":"Erin","family":"Sinai","sequence":"first","affiliation":[{"name":"School of Medicine, Creighton University  Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bridget E.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Division of Allergy and Immunology Phoenix Children's  Phoenix Arizona USA"},{"name":"Division of Allergy, Asthma, and Clinical Immunology Mayo Clinic  Scottsdale Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Pecak","sequence":"additional","affiliation":[{"name":"Division of Allergy and Immunology Phoenix Children's  Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shauna","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Phoenix Children's  Phoenix Arizona USA"},{"name":"Department of Child Health University of Arizona College of Medicine  Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward L.","family":"Swing","sequence":"additional","affiliation":[{"name":"Graduate Medical Education, Phoenix Children's  Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cindy","family":"Bauer","sequence":"additional","affiliation":[{"name":"Division of Allergy and Immunology Phoenix Children's  Phoenix Arizona USA"},{"name":"Department of Child Health University of Arizona College of Medicine  Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573396315666191022154432"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000934"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1397\u20103142.2003.00116.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12693"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100012.2012.01670.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12205"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20103046.2006.00538.x"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20103046.2007.00693.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12302"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.11.026"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2010.272"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.13723"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trim.2021.101"}],"container-title":["JGH 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