{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T07:19:06Z","timestamp":1787815146571,"version":"build-2784847793"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JGH Open"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      This study investigated the prevalence of\n                      <jats:italic>\n                        <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>\n                        elicobacter\n                        <jats:styled-content style=\"fixed-case\">pylori<\/jats:styled-content>\n                      <\/jats:italic>\n                      infection and associated factors in children from households with members' history of successful\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>H. pylori<\/jats:italic>\n                      <\/jats:styled-content>\n                      eradication.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A cross\u2010sectional study was conducted from February to December 2024 in Hanoi, Vietnam. Eligible households were those having lived together for at least 12\u2009months, including at least one child under 16\u2009years old and at least one member with successful\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>H. pylori<\/jats:italic>\n                      <\/jats:styled-content>\n                      eradication.\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>H. pylori<\/jats:italic>\n                      <\/jats:styled-content>\n                      infection status among family members was assessed using stool antigen testing. Data on household demographic characteristics, childcare practices, and infection status of family members were collected. Multivariable logistic regression was used to identify factors associated with infection in children.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 193 households with 877 members were included, including 338 children under 16\u2009years old. The prevalence of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>H. pylori<\/jats:italic>\n                      <\/jats:styled-content>\n                      infection was 59% overall and 53% among children. Children living with both infected parents had a higher infection prevalence than those with only one infected parent (58% vs. 38.2%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with a similar trend observed among infected siblings. After adjustment, parental infection status remained the strongest predictor of infection (aOR\u2009=\u20093.18; 95% CI: 1.83\u20135.52), while larger household size was inversely associated (aOR\u2009=\u20090.74; 95% CI: 0.58\u20130.93).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Children's infection risk increased according to the infection status of parents and siblings, while a higher number of family members was associated with a lower likelihood of infection, although this finding should be interpreted with caution, supporting the importance of household\u2010level transmission and family\u2010based prevention strategies in high\u2010prevalence settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jgh3.70453","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T03:50:49Z","timestamp":1785469849000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of\n                    <i>Helicobacter pylori<\/i>\n                    Infection in Children From Households With Members' History of Successful\n                    <i>H. pylori<\/i>\n                    Eradication"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6029-8690","authenticated-orcid":false,"given":"Trang Dinh","family":"Linh","sequence":"first","affiliation":[{"name":"School of Preventive Medicine and Public Health Hanoi Medical University  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5913-612X","authenticated-orcid":false,"given":"Van Hoang 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