{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T18:53:28Z","timestamp":1789412008945,"version":"build-2803163510"},"reference-count":68,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":5356,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Gene Med."],"published-print":{"date-parts":[[2001,9]]},"DOI":"10.1002\/jgm.210","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T21:24:42Z","timestamp":1030310682000},"page":"437-449","source":"Crossref","is-referenced-by-count":62,"title":["Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eyein vivo"],"prefix":"10.1002","volume":"3","author":[{"given":"Teresa","family":"Borr\ufffds","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B'Ann T.","family":"Gabelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon K.","family":"Klintworth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul L.","family":"Kaufman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001]]},"reference":[{"key":"10.1002\/jgm.210-BIB1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1136\/bjo.80.5.389","volume":"80","author":"Quigley","year":"1996","journal-title":"Br J Ophthalmol"},{"key":"10.1002\/jgm.210-BIB2","first-page":"1249","volume-title":"Principles and Practice of Ophthalmology","author":"Kupfer","year":"1994","unstructured":"Leading causes of visual impairment worldwide. In Principles and Practice of Ophthalmology, (eds). WB Saunders: Philadelphia, PA, 1994; 1249-1255."},{"key":"10.1002\/jgm.210-BIB3","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1001\/jama.1991.03470030069026","volume":"266","author":"Tielsch","year":"1991","journal-title":"JAMA"},{"key":"10.1002\/jgm.210-BIB4","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1001\/archopht.1997.01100160221012","volume":"115","author":"Leske","year":"1997","journal-title":"The Barbados Eye Study. Arch Ophthalmol"},{"key":"10.1002\/jgm.210-BIB5","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1001\/archopht.1994.01090170088028","volume":"112","author":"Quigley","year":"1994","journal-title":"Arch Ophthalmol"},{"key":"10.1002\/jgm.210-BIB6","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1016\/S0161-6420(92)31774-9","volume":"99","author":"Klein","year":"1992","journal-title":"Ophthalmology"},{"key":"10.1002\/jgm.210-BIB7","first-page":"1375","volume-title":"Glaucoma Therapy","author":"Goldberg","year":"1996","unstructured":"Compliance. In Glaucoma Therapy, (eds). CV Mosby: St Louis, MO, 1996; 1375-1384."},{"key":"10.1002\/jgm.210-BIB8","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF02385060","volume":"175","author":"Rohen","year":"1968","journal-title":"Albrecht Von Graefes Arch Klin Exp Ophthalmol"},{"key":"10.1002\/jgm.210-BIB9","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/S0161-6420(84)34241-5","volume":"91","author":"Polansky","year":"1984","journal-title":"Ophthalmology"},{"key":"10.1002\/jgm.210-BIB10","first-page":"1","volume":"14","author":"Bill","year":"1975","journal-title":"Invest Ophthalmol"},{"key":"10.1002\/jgm.210-BIB11","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1006\/exer.1999.0711","volume":"69","author":"Liu","year":"1999","journal-title":"Exp Eye Res"},{"key":"10.1002\/jgm.210-BIB12","first-page":"1282","volume":"37","author":"Borr\u00e1s","year":"1996","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1002\/jgm.210-BIB13","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/nm0696-649","volume":"2","author":"Bennett","year":"1996","journal-title":"Nat Med"},{"key":"10.1002\/jgm.210-BIB14","first-page":"1503","volume":"39","author":"Borr\u00e1s","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1002\/jgm.210-BIB15","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/sj.gt.3300860","volume":"6","author":"Borr\u00e1s","year":"1999","journal-title":"Gene Ther"},{"key":"10.1002\/jgm.210-BIB16","first-page":"2535","volume":"35","author":"Bennett","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1002\/jgm.210-BIB17","volume-title":"Methods in Molecular Biology","author":"Graham","year":"1991","unstructured":"Manipulation of adenoviral vectors. In Methods in Molecular Biology, (ed.). Humana Press: Clifton, NJ, 1991; 109-128."},{"key":"10.1002\/jgm.210-BIB18","first-page":"616","volume":"6","author":"Berkner","year":"1988","journal-title":"Biotechniques"},{"key":"10.1002\/jgm.210-BIB19","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0092-8674(92)90213-V","volume":"68","author":"Rosenfeld","year":"1992","journal-title":"Cell"},{"key":"10.1002\/jgm.210-BIB20","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1126\/science.2017680","volume":"252","author":"Rosenfeld","year":"1991","journal-title":"Science"},{"key":"10.1002\/jgm.210-BIB21","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/ng0596-54","volume":"13","author":"Kozarsky","year":"1996","journal-title":"Nat Genet"},{"key":"10.1002\/jgm.210-BIB22","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/ng0393-224","volume":"3","author":"Akli","year":"1993","journal-title":"Nat Genet"},{"key":"10.1002\/jgm.210-BIB23","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/1523-1747.ep12372181","volume":"102","author":"Setoguchi","year":"1994","journal-title":"J Invest Dermatol"},{"key":"10.1002\/jgm.210-BIB24","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/361647a0","volume":"361","author":"Ragot","year":"1993","journal-title":"Nature"},{"key":"10.1002\/jgm.210-BIB25","first-page":"2211","volume":"36","author":"Budenz","year":"1995","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1002\/jgm.210-BIB26","first-page":"2224","volume":"38","author":"Hoffman","year":"1997","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1002\/jgm.210-BIB27","first-page":"363","volume":"20","author":"Graham","year":"1992","journal-title":"Biotechnology"},{"key":"10.1002\/jgm.210-BIB28","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0167-7799(90)90144-M","volume":"8","author":"Graham","year":"1990","journal-title":"Trends Biotechnol"},{"key":"10.1002\/jgm.210-BIB29","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S1054-3589(08)60140-4","volume":"40","author":"Hitt","year":"1997","journal-title":"Adv Pharmacol"},{"key":"10.1002\/jgm.210-BIB30","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/ng0194-75","volume":"6","author":"Zabner","year":"1994","journal-title":"Nat Genet"},{"key":"10.1002\/jgm.210-BIB31","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/sj.gt.3300804","volume":"6","author":"Iwamoto","year":"1999","journal-title":"Gene Ther"},{"key":"10.1002\/jgm.210-BIB32","first-page":"192","volume":"1","author":"Yei","year":"1994","journal-title":"Gene Ther"},{"key":"10.1002\/jgm.210-BIB33","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1128\/JVI.69.4.2004-2015.1995","volume":"69","author":"Yang","year":"1995","journal-title":"J Virol"},{"key":"10.1002\/jgm.210-BIB34","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1089\/hum.1996.7.3-319","volume":"7","author":"Dong","year":"1996","journal-title":"Hum Gene Ther"},{"key":"10.1002\/jgm.210-BIB35","first-page":"117","volume":"3","author":"Kaplan","year":"1996","journal-title":"Gene Ther"},{"key":"10.1002\/jgm.210-BIB36","first-page":"103","volume":"3","author":"St George","year":"1996","journal-title":"Gene Ther"},{"key":"10.1002\/jgm.210-BIB37","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1172\/JCI119149","volume":"99","author":"Schulick","year":"1997","journal-title":"J Clin Invest"},{"key":"10.1002\/jgm.210-BIB38","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1089\/hum.1995.6.4-457","volume":"6","author":"Zsengeller","year":"1995","journal-title":"Hum Gene Ther"},{"key":"10.1002\/jgm.210-BIB39","doi-asserted-by":"crossref","first-page":"4407","DOI":"10.1073\/pnas.91.10.4407","volume":"91","author":"Yang","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1002\/jgm.210-BIB40","doi-asserted-by":"crossref","first-page":"4626","DOI":"10.1128\/JVI.71.6.4626-4637.1997","volume":"71","author":"Dedieu","year":"1997","journal-title":"J Virol"},{"key":"10.1002\/jgm.210-BIB41","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/sj.gt.3300404","volume":"4","author":"Wang","year":"1997","journal-title":"Gene Ther"},{"key":"10.1002\/jgm.210-BIB42","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1128\/JVI.72.2.926-933.1998","volume":"72","author":"Amalfitano","year":"1998","journal-title":"J Virol"},{"key":"10.1002\/jgm.210-BIB43","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0165-2478(97)00049-7","volume":"57","author":"Christ","year":"1997","journal-title":"Immunol Lett"},{"key":"10.1002\/jgm.210-BIB44","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1128\/JVI.72.3.2022-2032.1998","volume":"72","author":"Lusky","year":"1998","journal-title":"J Virol"},{"key":"10.1002\/jgm.210-BIB45","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1038\/sj.gt.3300995","volume":"6","author":"Parks","year":"1999","journal-title":"Gene Ther"},{"key":"10.1002\/jgm.210-BIB46","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000097271","volume":"3","author":"Taylor","year":"1996","journal-title":"Neuroimmunomodulation"},{"key":"10.1002\/jgm.210-BIB47","first-page":"766","volume":"14","author":"Kaufman","year":"1975","journal-title":"Invest Ophthalmol"},{"key":"10.1002\/jgm.210-BIB48","first-page":"793","volume":"15","author":"Kaufman","year":"1976","journal-title":"Invest Ophthalmol"},{"key":"10.1002\/jgm.210-BIB49","first-page":"558","volume":"15","author":"Kaufman","year":"1976","journal-title":"Invest Ophthalmol"},{"key":"10.1002\/jgm.210-BIB50","first-page":"135","volume":"3","author":"B\u00e1r\u00e1ny","year":"1964","journal-title":"Invest Ophthalmol"},{"key":"10.1002\/jgm.210-BIB51","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1001\/archopht.1980.01020030538022","volume":"98","author":"Kaufman","year":"1980","journal-title":"Arch Ophthalmol"},{"key":"10.1002\/jgm.210-BIB52","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/978-94-011-5698-1_35","volume-title":"Basic and Clinical Applications of Vision Science","author":"Croft","year":"1997","unstructured":"et al. Comparison of Goldmann tonometry measurements using creamer vs fluorescein in cynomolgus monkeys. In Basic and Clinical Applications of Vision Science, (ed.). Kluwer: Dordrecht, The Netherlands, 1997; 213-216."},{"key":"10.1002\/jgm.210-BIB53","volume-title":"Fluorescein Angiography of the Retina","author":"Wessing","year":"1969","unstructured":"Fluorescein Angiography of the Retina. CV Mosby: St Louis, MO, 1969."},{"key":"10.1002\/jgm.210-BIB54","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1089\/10430349950016401","volume":"10","author":"Brann","year":"1999","journal-title":"Hum Gene Ther"},{"key":"10.1002\/jgm.210-BIB55","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1128\/JVI.72.1.180-190.1998","volume":"72","author":"Loser","year":"1998","journal-title":"J Virol"},{"key":"10.1002\/jgm.210-BIB56","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1006\/bbrc.1999.0954","volume":"260","author":"Liu","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1002\/jgm.210-BIB57","first-page":"477","volume":"28","author":"Toris","year":"1987","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1002\/jgm.210-BIB58","first-page":"2568","volume":"40","author":"Sagara","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1002\/jgm.210-BIB59","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0958-1669(00)00080-X","volume":"11","author":"Wu","year":"2000","journal-title":"Curr Opin Biotechnol"},{"key":"10.1002\/jgm.210-BIB60","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1089\/hum.1993.4.6-759","volume":"4","author":"Engelhardt","year":"1993","journal-title":"Hum Gene Ther"},{"key":"10.1002\/jgm.210-BIB61","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1089\/hum.1993.4.6-771","volume":"4","author":"Simon","year":"1993","journal-title":"Hum Gene Ther"},{"key":"10.1002\/jgm.210-BIB62","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1089\/hum.1994.5.6-731","volume":"5","author":"Yei","year":"1994","journal-title":"Hum Gene Ther"},{"key":"10.1002\/jgm.210-BIB63","doi-asserted-by":"crossref","first-page":"6191","DOI":"10.1073\/pnas.87.16.6191","volume":"87","author":"Ginsberg","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1002\/jgm.210-BIB64","first-page":"477","volume":"28","author":"Toris","year":"1987","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1002\/jgm.210-BIB65","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1001\/archopht.117.6.794","volume":"117","author":"Sagara","year":"1999","journal-title":"Arch Ophthalmol"},{"key":"10.1002\/jgm.210-BIB66","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1006\/exer.1998.0508","volume":"67","author":"Ocklind","year":"1998","journal-title":"Exp Eye Res"},{"key":"10.1002\/jgm.210-BIB67","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0014-4835(89)90049-3","volume":"49","author":"Gabelt","year":"1989","journal-title":"Exp Eye Res"},{"key":"10.1002\/jgm.210-BIB68","first-page":"581","volume-title":"The Uveal Tract and its Endogenous Inflammations","author":"Rohen","year":"1965","unstructured":"Morphology of the uveal tract. In The Uveal Tract and its Endogenous Inflammations, (ed.). Little, Brown & Company: Boston, MA, 1965; 581-667."}],"container-title":["The Journal of Gene Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjgm.210","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/jgm.210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T07:40:22Z","timestamp":1625470822000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jgm.210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":68,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,9]]}},"URL":"https:\/\/doi.org\/10.1002\/jgm.210","relation":{},"ISSN":["1099-498X","1521-2254"],"issn-type":[{"value":"1099-498X","type":"print"},{"value":"1521-2254","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001]]}}}