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Here, we have discussed the case of a 51\u2010year\u2010old gentleman diagnosed with B\u2010myeloid mixed\u2010phenotype acute leukemia with t(9;22)(q34.1;q11.2); BCR\u2013ABL1p210, in complete hematological, cytogenetic, and molecular remission, who developed chylothorax. Though pleural effusion is a commonly observed adverse effect of dasatinib therapy, chylothorax is rare. The ability of Dasatinib to inhibit multiple families of tyrosine kinases could be considered the etiology. Discontinuation of the drug resolved the symptom, but pleural effusion recurred once Dasatinib was resumed. Chylothorax induced by Dasatinib is a differential to be kept in mind, owing to the limited number of cases being reported.<\/jats:p>","DOI":"10.1002\/jha2.226","type":"journal-article","created":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T03:45:51Z","timestamp":1621395951000},"page":"545-550","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Dasatinib\u2010induced chylothorax: An unusual presentation of a common adverse event\u2014A case report with literature review"],"prefix":"10.1002","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9290-0270","authenticated-orcid":false,"given":"Theresa","family":"Paul","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Hamad Medical Corporation  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil Yousaf","family":"Ellahie","sequence":"additional","affiliation":[{"name":"Department of Hematology National 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