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Unusual eosinophilia was disclosed in the patient's cerebrospinal fluid. After treatment with methylprednisolone and siltuximab, a decrease in clinical symptoms and magnetic resonance imaging lesions were obtained. This unprecedented presentation of eosinophilic meningitis after CAR\u2010T cells therapy highlights the need for a better understanding of the physiopathology of ICANS, especially to identify potentially targetable pathways.<\/jats:p>","DOI":"10.1002\/jha2.381","type":"journal-article","created":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T14:39:25Z","timestamp":1643726365000},"page":"533-536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Extensive myelitis with eosinophilic meningitis after Chimeric antigen receptor T cells therapy"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5148-3792","authenticated-orcid":false,"given":"Baptiste","family":"Le Calvez","sequence":"first","affiliation":[{"name":"Department of Hematology Nantes University hospital Nantes France"},{"name":"Pediatric Oncology Nantes University Hospital Nantes 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