{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:41:44Z","timestamp":1780360904781,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003958","name":"Stichting voor de Technische Wetenschappen","doi-asserted-by":"publisher","award":["CANCER\u2010ID"],"award-info":[{"award-number":["CANCER\u2010ID"]}],"id":[{"id":"10.13039\/501100003958","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["eJHaem"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Blood\u2010based biomarkers are gaining interest for response evaluation in classical Hodgkin lymphoma (cHL). However, it is unknown how blood\u2010based biomarkers relate to quantitative <jats:sup>18<\/jats:sup>F\u2010FDG\u2010PET features. We correlated extracellular vesicle\u2010associated miRNAs (EV\u2010miRNA), serum TARC, and complete blood count (CBC) with PET features (e.g., metabolic tumor volume [MTV], dissemination and intensity features) in 30 cHL patients at baseline. EV\u2010miR127\u20103p, EV\u2010miR24\u20103p, sTARC, and several CBC parameters showed weak to strong correlations with MTV and dissemination features, but not with intensity features. Two other EV\u2010miRNAs only showed weak correlations with PET features. Therefore, blood\u2010based biomarkers may be complementary to PET features, which warrants further exploration of combining these biomarkers in prognostic models.<\/jats:p>","DOI":"10.1002\/jha2.432","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T10:42:27Z","timestamp":1651142547000},"page":"908-912","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Blood\u2010circulating EV\u2010miRNAs, serum TARC, and quantitative FDG\u2010PET features in classical Hodgkin lymphoma"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3551-0038","authenticated-orcid":false,"given":"Esther E. 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J.","family":"van Eijndhoven","sequence":"additional","affiliation":[{"name":"Amsterdam UMC Location Vrije Universiteit Amsterdam Department of Pathology  Boelelaan Amsterdam The Netherlands"},{"name":"Cancer Center Amsterdam Imaging and Biomarkers  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils J.","family":"Groenewegen","sequence":"additional","affiliation":[{"name":"Amsterdam UMC Location Vrije Universiteit Amsterdam Department of Pathology  Boelelaan Amsterdam The Netherlands"},{"name":"Cancer Center Amsterdam Imaging and Biomarkers  Amsterdam The Netherlands"},{"name":"Exbiome B.V.  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