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She developed mild leukopenia \u223c2\u00a0weeks after the SARS\u2010CoV\u20102 mRNA vaccine sequence, with progressive symptoms after subsequent vaccines, eventually developing severe aplastic anaemia (SAA). While there have been several reports of vaccine\u2010related SAA, at time of submission, our case is the first reported to develop after the Moderna mRNA SARS\u2010CoV\u20102 vaccine, as well as the first to document the gradual development of SAA over the course of many vaccine exposures. Physicians should be cognizant of vaccine\u2010associated SAA, considering current widespread coronavirus disease 2019 vaccination efforts.<\/jats:p>","DOI":"10.1002\/jha2.443","type":"journal-article","created":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T04:49:00Z","timestamp":1651726140000},"page":"983-988","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Severe aplastic anaemia after serial vaccinations for SARS\u2010CoV\u20102, pneumococcus and seasonal influenza"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5893-5162","authenticated-orcid":false,"given":"Xiao","family":"Wang","sequence":"first","affiliation":[{"name":"Division of Hematology and Oncology Department of Medicine Hospital of the University of Pennsylvania  Philadelphia Pennsylvania 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