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The treatment goal for lower\u2010risk MDS is to correct cytopenias or their consequences, with the goal of maintaining or improving quality of life. Erythropoiesis\u2010stimulating agents (ESAs) play an important role in treating anemia. Individuals with MDS who have a 5q deletion are particularly sensitive to treatment with lenalidomide; however, this comprises the minority of patients with MDS. Luspatercept was recently approved in the United States and the European Union for the treatment of ESA\u2010refractory MDS with ring sideroblasts. Research into new treatment options, especially after ESA failure, is needed. In this review, we will focus on the current therapeutic options for MDS\u2010related anemia.<\/jats:p>","DOI":"10.1002\/jha2.523","type":"journal-article","created":{"date-parts":[[2022,8,13]],"date-time":"2022-08-13T06:40:33Z","timestamp":1660372833000},"page":"1091-1099","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Lower\u2010risk myelodysplastic syndromes: Current treatment options for anemia"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1708-8606","authenticated-orcid":false,"given":"Mathieu","family":"Meunier","sequence":"first","affiliation":[{"name":"Department of Haematology CHU Grenoble Alpes  Grenoble France"},{"name":"Institute for Advanced Bioscience Universit\u00e9 Grenoble Alpes  Grenoble 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