{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T02:55:01Z","timestamp":1789440901369,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["eJHaem"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>There is a lack of consensus on therapy sequencing in previously treated multiple myeloma, particularly after anti\u2010B\u2010cell maturation antigen (BCMA) therapy. Earlier reports on selinexor (X) regimens demonstrated considerable efficacy in early treatment, and after anti\u2010BCMA\u2010targeted chimeric antigen receptor\u2010T cell therapy. Here, we present data from 11 heavily pretreated patients who predominantly received BCMA\u2010antibody\u2010drug conjugate therapy. We observe that X\u2010containing regimens are potent and achieve durable responses with numerically higher overall response and clinical benefit rates, as well as median progression free survival compared to patients\u2019 prior anti\u2010BCMA therapies, despite being used later in the treatment course. In an area of evolving unmet need, these data reaffirm the efficacy of X\u2010based regimens following broader anti\u2010BCMA therapy.<\/jats:p>","DOI":"10.1002\/jha2.572","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T09:50:18Z","timestamp":1664531418000},"page":"1270-1276","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Selinexor\u2010based regimens in patients with multiple myeloma after prior anti\u2010B\u2010cell maturation antigen treatment"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0630-8458","authenticated-orcid":false,"given":"Muhamed","family":"Baljevic","sequence":"first","affiliation":[{"name":"Vanderbilt\u2010Ingram Cancer Center Vanderbilt University Medical Center  Nashville Tennessee 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