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In addition, during the same period, 64 patients with stage IE\/IIE1 disease who received conventional treatment were selected as the control group. The most common primary sites were the ocular adnexal area (17 cases), followed by the salivary glands (four cases), pulmonary (three cases), and thyroid, trachea, larynx, and colon region (one case each). First\u2010line antibiotic treatment resulted in an overall response rate of 57.1%: 12 patients achieved complete remission (CR), while four achieved partial remission (antibiotic\u2010responsive tumors). Monoclonal gammopathy was significantly prevalent in antibiotic\u2010unresponsive tumors than in antibiotic\u2010responsive tumors (50.0% [6\/12] vs. 12.5% [2\/16], <jats:italic>p<\/jats:italic>\u00a0=\u00a00.044). After a median follow\u2010up of 7\u00a0years, all patients with CR remained lymphoma\u2010free, with 7\u2010year event\u2010free survival (EFS) and overall survival (OS) rates of 62.7% and 96.4%, respectively. The 7\u2010year EFS and OS rates of patients who received conventional treatments were 73.1% and 91.1%, respectively. Compared with that noted in patients who received conventional treatment, antibiotic treatment was effective in some patients with localized extragastric MALT lymphoma.<\/jats:p>","DOI":"10.1002\/jha2.608","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T04:54:23Z","timestamp":1667796863000},"page":"55-66","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["First\u2010line antibiotic treatment in patients with localized extragastric mucosa\u2010associated lymphoid tissue lymphoma"],"prefix":"10.1002","volume":"4","author":[{"given":"Ming","family":"Yao","sequence":"first","affiliation":[{"name":"Department of Internal Medicine National Taiwan University Hospital and National Taiwan University College of Medicine  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu\u2010Lang","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of 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