{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T14:46:19Z","timestamp":1781880379262,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T00:00:00Z","timestamp":1668297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["eJHaem"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Due to relatively high nonrelapse mortality (NRM), allogeneic hematopoietic stem cell transplantation (allo\u2010HSCT) in non\u2010Hodgkin's lymphoma (NHL) remains the ultimate line of treatment but the only curable approach in a setting of relapse\/refractory disease. Here, we conducted a retrospective, multicenter, registry\u2010based analysis on patients who underwent allo\u2010HSCT for NHL in Switzerland, over 30\u2010year (1985\u20132020) period. The study included 301 allo\u2010HSCTs performed for NHL patients in three University Hospitals of Switzerland (Zurich, Basel and Geneva) 09\/1985 to 05\/2020. We assessed in univariate and multivariable analysis the impact on survivals (overall survival [OS], relapse free survival [RFS], relapse incidence [RI], and non\u2010treatment related mortality [NRM]). The maximum follow\u2010up was 25 years with median follow\u2010up for alive patients of 61 months. The median age at allo\u2010HSCT was 51 years. Three\u2010 and \u2010year\u00a0OS was \u2010 59.5% and 55.4%; 3\u2010 and 5\u2010year PFS was 50% and 44%; 3\u2010 and 5\u2010year NRM was 21.7% and 23.6%. RI at 3 and 5 years was 27.4% and 34.9%. In conclusion, our analysis of the entire Swiss experience of allo\u2010HSCT in patients with NHL shows promising 5\u2010 and possibly 10\u2010year OS and relatively acceptable NRM rates for such population, the majority being not in complete remission (CR) at the time of transplantation.<\/jats:p>","DOI":"10.1002\/jha2.614","type":"journal-article","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T02:29:48Z","timestamp":1668392988000},"page":"258-261","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Allogeneic hematopoietic stem cell transplantation in non\u2010Hodgkin lymphoma in Switzerland, 30 years of experience: Sooner is better"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9478-4069","authenticated-orcid":false,"given":"Ekaterina","family":"Rebmann","sequence":"first","affiliation":[{"name":"Department of Hematology University Hospital of Bern (Inselspital)  Bern Switzerland"},{"name":"Department of Oncology\u2010Hematology Hospital of Neuch\u00e2tel (RHNE)  Neuch\u00e2tel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitja","family":"Nabergoj","sequence":"additional","affiliation":[{"name":"Department of Hematology L'H\u00f4pital Riviera\u2010Chablais  Vaud\u2010Valais Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastien","family":"Grandjean","sequence":"additional","affiliation":[{"name":"Department of Hematology University Hospital of Bern (Inselspital)  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paraskevi","family":"Stakia","sequence":"additional","affiliation":[{"name":"Department of Hematology Geneva University Hospitals (HUG)  Gen\u00e8ve Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alix","family":"Stern","sequence":"additional","affiliation":[{"name":"Department of Oncology\u2010Hematology Hospital of Neuch\u00e2tel (RHNE)  Neuch\u00e2tel Switzerland"},{"name":"Faculty of Medicine University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0427-7747","authenticated-orcid":false,"given":"Michael","family":"Medinger","sequence":"additional","affiliation":[{"name":"Department of Hematology University Hospital of Basel (USB)  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavroula","family":"Masouridi\u2010Levrat","sequence":"additional","affiliation":[{"name":"Department of Hematology Geneva University Hospitals (HUG)  Gen\u00e8ve Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Dantin","sequence":"additional","affiliation":[{"name":"Department of Hematology Geneva University Hospitals (HUG)  Gen\u00e8ve Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs","family":"Schanz","sequence":"additional","affiliation":[{"name":"Department of Hematology University Hospital of Zurich (UZH)  Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Baldomero","sequence":"additional","affiliation":[{"name":"Department of Hematology University Hospital of Basel (USB)  Basel Switzerland"},{"name":"SBST Data Registry Office Univesiry Hospital of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Passweg","sequence":"additional","affiliation":[{"name":"Department of Hematology University Hospital of Basel (USB)  Basel Switzerland"},{"name":"Faculty of Medicine University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gayathri","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Hematology University Hospital of Zurich (UZH)  Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7757-4753","authenticated-orcid":false,"given":"Alicia","family":"Rovo","sequence":"additional","affiliation":[{"name":"Department of Hematology University Hospital of Bern (Inselspital)  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Chalandon","sequence":"additional","affiliation":[{"name":"Department of Hematology Geneva University Hospitals (HUG)  Gen\u00e8ve Switzerland"},{"name":"Faculty of Medicine University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2019.03.005"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11899-016-0319-0"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-01-791335"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2014.198"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.49.2454"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.46.0188"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-010-0986-1"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hon.2201"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-019-0465-9"},{"issue":"19","key":"e_1_2_11_11_1","first-page":"2646","article-title":"A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first\u2010line therapy in poor\u2010risk peripheral T\u2010NHL","volume":"137","author":"Schmitz N","year":"2021","journal-title":"Blood"},{"key":"e_1_2_11_12_1","unstructured":"Institute for Quality and Efficiency in Health Care.Allogeneic stem cell transplantation in aggressive B\u2010cell non\u2010Hodgkin lymphoma and in T\u2010cell non\u2010Hodgkin lymphoma IQWiG Reports \u2010 Commission No N17\u201002. Cologne (Germany):Institute for Quality and Efficiency in Health Care;2019."},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-019-03835-3"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beha.2018.07.011"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30864-7"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31366-0"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020009098"}],"container-title":["eJHaem"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jha2.614","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jha2.614","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jha2.614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T13:56:04Z","timestamp":1710338164000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jha2.614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,13]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1002\/jha2.614"],"URL":"https:\/\/doi.org\/10.1002\/jha2.614","archive":["Portico"],"relation":{},"ISSN":["2688-6146","2688-6146"],"issn-type":[{"value":"2688-6146","type":"print"},{"value":"2688-6146","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,13]]},"assertion":[{"value":"2022-10-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}