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We report a case of acute lung injury in a healthy donor after G\u2010CSF administration requiring hospitalization and treatment with corticosteroids. This case highlights the potential for rare but serious G\u2010CSF\u2010induced pulmonary toxicity, particularly in donors with predisposing factors such as obesity and smoking. Increased awareness of these rare adverse events is essential given the widespread use of G\u2010CSF in PBSC mobilization.<\/jats:p>","DOI":"10.1002\/jha2.70102","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T16:44:15Z","timestamp":1752165855000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Acute Lung Injury in a Healthy Peripheral Blood Stem Cell Donor Following Granulocyte\u2010colony Stimulating Factor Administration: A Case Report"],"prefix":"10.1002","volume":"6","author":[{"given":"Nihar","family":"Desai","sequence":"first","affiliation":[{"name":"Hans Messner Allogeneic Blood and Marrow Transplant Program Division of Medical Oncology and Hematology Princess Margaret Hospital  Toronto Canada"},{"name":"Temerty Faculty of Medicine University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommy Alfaro","family":"Moya","sequence":"additional","affiliation":[{"name":"Hans Messner Allogeneic Blood and Marrow Transplant Program Division of Medical Oncology and Hematology Princess Margaret Hospital  Toronto Canada"},{"name":"Temerty Faculty of Medicine University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Heffering\u2010Cardwell","sequence":"additional","affiliation":[{"name":"Hans Messner Allogeneic Blood and Marrow Transplant Program Division of Medical Oncology and Hematology Princess Margaret Hospital  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe Tijmes","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2956-0848","authenticated-orcid":false,"given":"Fotios 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