{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T10:59:14Z","timestamp":1761389954517,"version":"build-2065373602"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["eJHaem"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>With the purpose of identifying unmet needs of patients with acute leukemia, survivors were identified from the Swedish National Acute Leukemia registries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>At six months and at two years from diagnosis, patients were requested by mail to report outcome with focus on depression, sick leave, and sexual dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 910 patients alive at 6 months, 474 (52%) participated, and of 331 alive at two years, 250 (76%) participated. At two years, the majority \u226465 years, 52%, had returned to work &gt;30\u00a0h\/week, and 40% were still on medical leave. Economic hardship was common, especially in the latter group. Impaired sexual function, impact on sexual desire, as well as anxiety about infections, were frequently reported. Depression with a PHQ\u20108 score \u226510 was more prevalent in patients \u226465 years than in older patients. In younger patients, a PHQ\u20108 score \u226510 was associated with sexual dysfunction, economic hardship, single living, and anxiety of infections, whereas in patients &gt;65 years, single living and economic hardship remained significant. No impact of the Covid\u201019 pandemic on depression was found.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The use of depression screening instruments and awareness of sexual dysfunction could be of importance in the routine care of acute leukemia patients two years after diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>The authors have confirmed clinical trial registration is not needed for this submission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jha2.70142","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T08:59:07Z","timestamp":1756803547000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High Prevalence of Psychological Symptoms, Sexual Dysfunction, and Prolonged Medical Leave Two Years After Acute Leukemia Diagnosis\u2014Patient Reported Outcome in Sweden"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1737-5568","authenticated-orcid":false,"given":"Emma Bergfelt","family":"Lennmyr","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, Haematology Uppsala University  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"L\u00fcbking","sequence":"additional","affiliation":[{"name":"Department of Haematology, Oncology and Radiation Physics Sk\u00e5ne University Hospital  Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Abrahamsson","sequence":"additional","affiliation":[{"name":"Regional Cancer Centre Stockholm\u2010Gotland  Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar","family":"Juliusson","sequence":"additional","affiliation":[{"name":"Department of Haematology, Oncology and Radiation Physics Sk\u00e5ne University Hospital  Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"H\u00f6glund","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Haematology Uppsala University  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hel\u00e9ne","family":"Hallb\u00f6\u00f6k","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Haematology Uppsala University  Uppsala 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