{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T09:10:22Z","timestamp":1789463422707,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["eJHaem"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Sporadic late\u2010onset nemaline myopathy (SLONM) is a rare, acquired myopathy often associated with monoclonal gammopathy. We report a 48\u2010year\u2010old man presenting with progressive proximal and truncal muscle weakness in whom SLONM associated with smoldering myeloma was highly suspected. He received daratumumab, lenalidomide, and dexamethasone followed by high\u2010dose melphalan with autologous stem cell transplantation and posttransplant therapy. Treatment resulted in marked improvement in muscle strength and performance status. The patient achieved minimal residual disease negativity and has remained relapse\u2010free for 5 years. This case highlights the potential efficacy of daratumumab\u2010based therapy followed by transplantation in SLONM associated with plasma cell dyscrasia.<\/jats:p>\n                  <jats:p>Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.<\/jats:p>","DOI":"10.1002\/jha2.70390","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T08:10:34Z","timestamp":1789459834000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Myeloma\u2010Associated Sporadic Late\u2010Onset Nemaline Myopathy, Successfully Treated with Daratumumab Based Induction and Autologous Stem Cell Transplantation: A Case Report"],"prefix":"10.1002","volume":"7","author":[{"given":"Kenji","family":"Moriwaki","sequence":"first","affiliation":[{"name":"Department of Hematology Rheumatology and Infectious Diseases Graduate School of Medical Sciences Kumamoto University  Kumamoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawara","family":"Kawano","sequence":"additional","affiliation":[{"name":"Department of Hematology Rheumatology and Infectious Diseases Graduate School of Medical Sciences Kumamoto University  Kumamoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Neurology Graduate School of Medical Sciences Kumamoto University  Kumamoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nao","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Hematology Rheumatology and Infectious Diseases Graduate School of Medical Sciences Kumamoto University  Kumamoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuharu","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Neurology Graduate School of Medical Sciences Kumamoto University  Kumamoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun\u2010ichirou","family":"Yasunaga","sequence":"additional","affiliation":[{"name":"Department of Hematology Rheumatology and Infectious Diseases Graduate School of Medical Sciences Kumamoto University  Kumamoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025\u20106196(25)07928\u20105"},{"key":"e_1_2_11_3_1","first-page":"308","article-title":"Late\u2010Onset Rod Myopathy: A Newly Recognized Acquired and Progressive Disease","volume":"16","author":"Engel W. 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