{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:54:07Z","timestamp":1791258847423,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["eJHaem"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>TAFRO syndrome is a rare inflammatory disorder whose hepatic manifestations may mimic decompensated cirrhosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Cases:<\/jats:title>\n                    <jats:p>We report two women with TAFRO syndrome associated with portal\u2010sinusoidal vascular disorder (PSVD), a rare cause of non\u2010cirrhotic portal hypertension. In both cases, liver biopsy excluded cirrhosis and confirmed PSVD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Clinical outcomes were markedly different. One patient achieved sustained disease control with anti\u2010IL\u20106 therapy and remained stable for more than 6 years, whereas the other developed rapidly progressive and fatal disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PSVD may represent an underrecognized hepatic manifestation of TAFRO syndrome. Recognizing this association may facilitate earlier diagnosis, avoid misclassification as cirrhosis, and support timely therapeutic management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>The authors have confirmed clinical trial registration is not needed for this submission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jha2.70414","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:45:12Z","timestamp":1791258312000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["When Liver Disease Misleads the Diagnosis: Two Cases of TAFRO Syndrome With Porto\u2010Sinusoidal Vascular Disease"],"prefix":"10.1002","volume":"7","author":[{"given":"Laura","family":"Dassy","sequence":"first","affiliation":[{"name":"Haematology Department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Poletti","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology CHU UCL Namur Universit\u00e9 Catholique de Louvain  Yvoir Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaoutar","family":"Hafraoui","sequence":"additional","affiliation":[{"name":"Haematology Department Hospital Regional of Verviers  Verviers Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Lejeune","sequence":"additional","affiliation":[{"name":"Haematology Department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Somja","sequence":"additional","affiliation":[{"name":"Pathology Department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Collins","sequence":"additional","affiliation":[{"name":"Pathology Department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Guiot","sequence":"additional","affiliation":[{"name":"Pneumology Department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Theate","sequence":"additional","affiliation":[{"name":"Pathology Department CHU UCL Namur  Yvoir Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo","family":"Caers","sequence":"additional","affiliation":[{"name":"Haematology Department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Delwaide","sequence":"additional","affiliation":[{"name":"Gastroenterology Department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Marot","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology CHU UCL Namur Universit\u00e9 Catholique de Louvain  Yvoir Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Putzeys","sequence":"additional","affiliation":[{"name":"Gastroenterology Department Regional Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga\u00eblle","family":"Vertenoeil","sequence":"additional","affiliation":[{"name":"Haematology Department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277\u2010022\u201004762\u20106"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.17868"},{"key":"e_1_2_11_4_1","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1554198","article-title":"Case Report: TAFRO Syndrome Misdiagnosed as Liver Cirrhosis Due to Persistent Abdominal Distension","volume":"16","author":"Ma L.","year":"2025","journal-title":"Frontiers in 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