{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T13:12:52Z","timestamp":1788786772412,"version":"build-2803163510"},"reference-count":6,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T00:00:00Z","timestamp":1687478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["eJHaem"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic myelomonocytic leukemia (CMML) is a myelodysplastic\/myeloproliferative neoplasm characterized by the infiltration of blood and bone marrow by immature monocytes, in which extra\u2010hematopoietic localization is uncommon. We report the case of a 69\u2010year\u2010old\u2010man with highly likely ectopic brain CMML involvement by MRI. Without the possibility of cerebral biopsy and with a negative infectious disease assessment, high\u2010dose cytarabine\u2010based chemotherapy was successfully administered. The favorable evolution in this case highlights the potential benefit of such treatment, even without a cerebral biopsy to confirm the disease. This case can aid clinical decision\u2010making in the future.<\/jats:p>","DOI":"10.1002\/jha2.740","type":"journal-article","created":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T00:24:09Z","timestamp":1687652649000},"page":"844-847","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cerebral localization of chronic myelomonocytic leukemia and improvement with high\u2010dose cytarabine: A case report"],"prefix":"10.1002","volume":"4","author":[{"given":"Cl\u00e9mence","family":"Ham\u00e9on","sequence":"first","affiliation":[{"name":"Hematology and Cell Therapy Department Tours University Hospital  Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Machet","sequence":"additional","affiliation":[{"name":"Hematology and Cell Therapy Department Tours University Hospital  Tours 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