{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:34:26Z","timestamp":1792632866407,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T00:00:00Z","timestamp":1651276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background\/Purpose<\/jats:title>\n                    <jats:p>Whether organ\u2010preserving pancreatic surgery has an advantage in postoperative short\u2010 and long\u2010term outcomes or not is still unknown because only small case series studies have been available to date. In this multicenter retrospective study, we aimed to elucidate the clinical advantage and disadvantage of organ\u2010preserving pancreatectomy among patients with low\u2010grade malignant pancreatic tumors and benign pancreatic diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included patients diagnosed with benign or low\u2010malignant pancreatic tumor who underwent pancreaticoduodenectomy (PD) in 621 cases, duodenum\u2010preserving pancreatic head resection (DPPHR) in 31 cases, middle pancreatectomy (MP) in 148 cases, distal pancreatectomy (DP) in 814 cases, and spleen\u2010preserving distal pancreatectomy (SPDP) in 259 cases between January 1, 2013, and December 31, 2017. Preoperative backgrounds, surgical outcomes and pre\u2010 and postoperative (3, 6, 12, 24, and 36\u00a0months) nutritional status were compared between these procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In terms of short\u2010term outcomes, the incidence of pancreatic fistula in patients who underwent MP was significantly higher than in patients with standard pancreatectomy. As for the long\u2010term pancreatic functions in the cases of head or body lesion, both exocrine and endocrine functions after MP were significantly favorable compared with the PD group from 3 to 36\u00a0months after surgery. In pancreatic body or tail lesion, significant advantage of endocrine function, but not exocrine function, was found in the MP group compared to standard DP at all time points.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>MP may contribute to the improvement of postoperative quality of life for patients with pancreatic body low\u2010malignant tumors, rather than PD or DP; however, reducing the incidence of short\u2010term complications such as pancreatic fistula is a future challenge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jhbp.1154","type":"journal-article","created":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T07:43:15Z","timestamp":1650354195000},"page":"898-910","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Clinical outcomes of organ\u2010preserving pancreatectomy for benign or low\u2010grade malignant pancreatic tumors: A multicenter nationwide survey in Japan"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6194-2507","authenticated-orcid":false,"given":"Yukio","family":"Asano","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery Fujita Health University Bantane Hospital  Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5798-2725","authenticated-orcid":false,"given":"Hiroyuki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Fujita Health University Bantane Hospital  Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Arakawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Fujita Health University Bantane Hospital  Aichi 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Graduate School of Medicine  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshifumi","family":"Takeyama","sequence":"additional","affiliation":[{"name":"Department of Surgery Kindai University Faculty of Medicine  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Ohtsuka","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Graduate School of Medicine Chiba University  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5520-8114","authenticated-orcid":false,"given":"Itaru","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Yokohama City University  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadahiro","family":"Takada","sequence":"additional","affiliation":[{"name":"Department of Surgery Teikyo University School of Medicine  Tokyo 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