{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:20:12Z","timestamp":1774952412834,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T00:00:00Z","timestamp":1656028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Purpose<\/jats:title><jats:p>Compared with currently available duodenoscopy\u2010assisted systems, direct peroral cholangioscopy (DPOC) using an ultra\u2010slim endoscope is limited by technical difficulties. The multibending (MB) ultra\u2010slim endoscope was introduced as a dedicated cholangioscope for DPOC to challenge the technical problem. We retrospectively analyzed the clinical utility of DPOC using an MB endoscope with free\u2010hand insertion into the bile duct in patients with biliary diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 145 patients who underwent DPOC using an MB endoscope were analyzed. The primary outcome was the technical success rate of DPOC using the free\u2010hand insertion of the MB endoscope. The secondary outcomes were the technical success rates of DPOC\u2010guided diagnostic and therapeutic interventions, the diagnostic accuracy of DPOC\u2010guided target biopsy, and adverse events related to DPOC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Free\u2010hand biliary insertion of a MB endoscope for DPOC was technically successful in 133 patients (91.7%). DPOC\u2010guided target biopsy was successful in 36 of 38 patients (94.7%) and had a diagnostic accuracy of 91.7% (95% confidence interval, 82.6\u2010100). Sixty\u2010nine therapeutic interventions were performed; technical success was achieved in 65 (94.2%). No severe adverse events were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The MB ultra\u2010slim endoscope was technically effective to perform a DPOC including various diagnosis and therapeutic interventions without device assistance. MB endoscope is considered to contribute to expanding a role of DPOC in diagnosis and treatment of diverse biliary tract diseases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.1189","type":"journal-article","created":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T18:24:02Z","timestamp":1654280642000},"page":"1292-1299","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy and safety of direct peroral cholangioscopy using a new multibending ultra\u2010slim endoscope for the management of biliary diseases"],"prefix":"10.1002","volume":"29","author":[{"given":"Yun Nah","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Digestive Disease Center and Research Institute SoonChunHyang University School of Medicine  Bucheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3946-9944","authenticated-orcid":false,"given":"Jong Ho","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Digestive Disease Center and Research Institute SoonChunHyang University School of Medicine  Bucheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Digestive Disease Center and Research Institute SoonChunHyang University School of Medicine  Cheonan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hae Won","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Digestive Disease Center and Research Institute SoonChunHyang University School of Medicine  Bucheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Kook","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Digestive Disease Center and Research Institute SoonChunHyang 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