{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:58:06Z","timestamp":1767909486336,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T00:00:00Z","timestamp":1717632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Endoscopic retrograde cholangiography (ERC)\u2010related procedures, usually performed before biliary tract cancer (BTC) surgery, are associated with increased risk for various complications, which can cause sarcopenia. No study has previously elucidated the relationship between preoperative ERC\u2010related procedures and sarcopenia\/skeletal muscle mass loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with BTC who underwent radical surgical resection following ERC\u2010related procedures were included. Skeletal muscle mass was evaluated using the psoas muscle mass index (PMI), which was determined using computed tomography images, and the change in PMI before the initial pre\u2010ERC and surgery (\u0394PMI) was calculated. Risk factors for advanced skeletal muscle mass loss, defined as a large \u0394PMI, were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study cohort included 90 patients with a median age of 72 (interquartile range, 65\u201375) years. The median PMI pre\u2010ERC and surgery was 4.40 and 4.15\u2009cm<jats:sup>2<\/jats:sup>\/m<jats:sup>2<\/jats:sup>, respectively (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01). The median \u0394PMI was \u22126.2% (interquartile range, \u221210.9% to 0.5%). By multivariate analysis, post\u2010ERC pancreatitis and cholangitis before surgery were independent predictive factors for large PMI loss (odds ratio, 4.57 and 3.18, respectively; <jats:italic>p<\/jats:italic>\u2009=\u2009.03 and <jats:italic>p<\/jats:italic>\u2009=\u2009.02, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Skeletal muscle mass decreases preoperatively in most patients with BTC undergoing ERC. Post\u2010ERC pancreatitis and cholangitis before surgery were independent risk factors for large skeletal muscle mass loss.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.12006","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T03:46:24Z","timestamp":1717731984000},"page":"549-558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Preoperative risk factors for skeletal muscle mass loss in patients with biliary tract cancer"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4156-8025","authenticated-orcid":false,"given":"Ryo","family":"Sugiura","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine Hokkaido University  Sapporo 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