{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:16:02Z","timestamp":1785770162086,"version":"3.56.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T00:00:00Z","timestamp":1734912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173365"],"award-info":[{"award-number":["82173365"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Serum phosphorus and serum calcium are important electrolytes in the body. The relationship between them and acute pancreatitis (AP) has been previously discussed. However, the results seem to lack credibility due to the neglect of mutual influence between them. Thus, a comprehensive indicator is needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study, AP patients with intensive care unit (ICU) treatment were extracted from Medical Information Mart for Intensive Care (MIMIC) database. The outcomes included in\u2010hospital mortality and ICU mortality. Kaplan\u2013Meier survival analysis, Cox proportional hazard regression model and restricted cubic spline were employed to investigate the association between the phosphorus\u2010to\u2010calcium ratio (PCR) index and clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 719 AP patients (57.2% male) were enrolled. The in\u2010hospital and ICU mortality were 11.4% and 7.5%, respectively. After adjusting for confounders, Cox proportional hazard analysis indicated patients with a higher PCR index had a significant association with in\u2010hospital mortality (adjusted hazard ratio, 2.88; 95% confidence interval, 1.34\u20136.19; <jats:italic>p<\/jats:italic>\u2009=\u2009.007). Restricted cubic splines revealed that a progressively increasing risk of all\u2010cause mortality was associated with an elevated PCR index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The PCR index has a strong correlation with in\u2010hospital and ICU all\u2010cause mortality in AP, which provides a reference for clinical decision\u2010making.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.12094","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T09:59:57Z","timestamp":1734947997000},"page":"228-237","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association between phosphorus\u2010to\u2010calcium ratio at <scp>ICU<\/scp> admission and all\u2010cause mortality in acute pancreatitis: Insights from the <scp>MIMIC<\/scp>\u2010<scp>IV<\/scp> database"],"prefix":"10.1002","volume":"32","author":[{"given":"Yimin","family":"Han","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an Shaanxi People's Republic of China"},{"name":"Pancreatic Disease Center of Xi'an Jiaotong University  Xi'an Shaanxi People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1951-666X","authenticated-orcid":false,"given":"Fan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an Shaanxi People's Republic of China"},{"name":"Pancreatic Disease Center of Xi'an Jiaotong University  Xi'an Shaanxi People's Republic of 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