{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:41:06Z","timestamp":1787319666829,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Study Aim<\/jats:title>\n                    <jats:p>\n                      Endoscopic papillectomy (EP) is widely performed for avoiding high\u2010risk surgeries. However, recurrence rates are high, and lateral extension is a risk for recurrence. With endoscopic submucosal dissection (ESD), even lesions with lateral extensions are able to be\n                      <jats:italic>en bloc<\/jats:italic>\n                      resected, and may reduce that risk. The aim of this study is to validate the adequacy and safety of the new strategy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>This is an exploratory observational study with prospective case enrollment and retrospective analysis. Inclusion criteria: patients aged 20\u201385\u2009years with a diagnosis of ampullary tumor or superficial nonampullary duodenal epithelial tumors extending into papilla, and endoscopically resected between December 2020 and April 2023. EP was performed with a lateral extension of &lt;\u200920\u2009mm, and ESD was performed with 20\u2009mm or more, and the validity of these strategies was verified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 40 patients were enrolled, 29 EP and 11 ESD underwent. The\n                      <jats:italic>en bloc<\/jats:italic>\n                      resection rate was 95% (38\/40) and endoscopic control was 97.5% (39\/40). Adverse events were observed in 27.5% (11\/40), with no significant difference in both groups. No serious adverse event was observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This strategy based on lateral extension performed very well, and ESD is a useful treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jhbp.12165","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T07:24:52Z","timestamp":1749453892000},"page":"706-712","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["New Endoscopic Strategy for Ampullary Tumor and Superficial Nonampullary Duodenal Epithelial Tumor Extending Into Papillary Area"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3713-3072","authenticated-orcid":false,"given":"Takashi","family":"Hirose","sequence":"first","affiliation":[{"name":"Department of 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