{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T15:40:27Z","timestamp":1774280427144,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T00:00:00Z","timestamp":1749081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The role of the ventrally positioned right hepatic artery (RHA) in congenital biliary dilatation (CBD) remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 1464 pediatric CBD patients undergoing surgery from 2015 to 2023, comparing those with ventrally positioned versus normal RHA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ventrally positioned RHA was identified in 10.31% of patients and was associated with more frequent symptoms (e.g., abdominal pain, vomiting, jaundice), elevated liver enzymes, and a higher incidence of liver fibrosis (23.40% vs. 14.85%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008). It was an independent risk factor for fibrosis (adjusted OR\u2009=\u20091.74,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011) and correlated with increased bile duct strictures and intrahepatic duct dilation. No recurrence was observed during a 41\u2010month median follow\u2010up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Ventrally positioned RHA contributes to biliary obstruction and liver fibrosis in pediatric CBD. Early recognition and surgical correction may improve outcomes and reduce long\u2010term complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jhbp.12171","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T05:20:19Z","timestamp":1749100819000},"page":"641-648","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Anatomical Variations of Right Hepatic Artery on Biliary Obstruction and Liver Fibrosis in Pediatric Congenital Biliary Dilatation Patients: A Retrospective Analysis of 1464 Cases"],"prefix":"10.1002","volume":"32","author":[{"given":"Jianfeng","family":"Luo","sequence":"first","affiliation":[{"name":"Capital Institute of Pediatrics Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Beijing China"},{"name":"Department of General Surgery, Capital Center for Children's Health Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaikun","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Capital Center for Children's Health Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anxiao","family":"Ming","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Capital Center for Children's Health Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haibin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Capital Center for Children's Health Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Diao","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Capital Center for Children's Health Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0358-3929","authenticated-orcid":false,"given":"Long","family":"Li","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Capital Center for Children's Health Capital Medical University  Beijing China"},{"name":"Department of Pediatric Surgery Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital  Beijing China"},{"name":"Research Unit of Minimally Invasive Pediatric Surgery on Diagnosis and Treatment Chinese Academy of Medical Sciences 2021RU015  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v25.i26.3334"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2014.04.023"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-195104000-00009"},{"issue":"9","key":"e_1_2_8_5_1","first-page":"AC01","article-title":"Variations in the Origin and Course of Right Hepatic Artery and Its Surgical Significance","volume":"10","author":"Mugunthan N.","year":"2016","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/412595"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/403104"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i19.3008"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2019.1632926"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2021.105667"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-015-4697-5"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.415"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.11.008"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.27932"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-023-05486-y"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.06.011"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-020-02376-2"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.12.022"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-013-3333-5"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.1994.35.2.231"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01655064"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.4103\/jiaps.JIAPS_199_17"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2005.01.023"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2011.11.015"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjac492"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-010-0294-0"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-017-4083-6"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-019-04489-y"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-022-02516-5"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/ases.13264"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2021.106300"}],"container-title":["Journal of Hepato-Biliary-Pancreatic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jhbp.12171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T13:55:40Z","timestamp":1762610140000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jhbp.12171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,5]]},"references-count":30,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1002\/jhbp.12171"],"URL":"https:\/\/doi.org\/10.1002\/jhbp.12171","archive":["Portico"],"relation":{},"ISSN":["1868-6974","1868-6982"],"issn-type":[{"value":"1868-6974","type":"print"},{"value":"1868-6982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,5]]},"assertion":[{"value":"2025-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}