{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:27:49Z","timestamp":1789165669263,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purposes<\/jats:title>\n                    <jats:p>Regional lymphadenectomy is standard in pancreatic cancer. The aim was to explore clinical impact for the prognostic index of nodal stations and optimal extent of lymphadenectomy in pancreatic cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 507 consecutive pancreatic cancer patients who underwent a surgery\u2010first approach and unified systemic lymphadenectomy were enrolled. The prognostic index of nodal stations was calculated by tumor location and relevant lymph node (LN) station, and clinicopathological factors and survival outcomes were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In the pancreatic head, LN13 dissection showed the highest prognostic index, with extremely low indices for LN6 and LN12 dissection. In the pancreatic body, LN11 dissection showed the highest index; LN9 and LN10 dissection both had indices of zero. In the pancreatic tail, LN11 dissection showed the highest index, and that for LN8 dissection was zero. Subgroup analyses of the prognostic index according to resectability status, peritoneal cytology, pathological stage, and the administration of postoperative adjuvant therapy were performed, and the overall pattern remained unchanged.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Regional lymphadenectomy is basically indispensable, considering LN metastasis, and the prognostic index of nodal stations showed the clinical impact on survival analysis. Also, it might be possible to omit some LN dissection based on the tumor location.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jhbp.12179","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T00:35:42Z","timestamp":1750898142000},"page":"667-678","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical Impact for Prognostic Index of Nodal Stations and Reconsideration of Optimal Regional Lymph Node Station in Pancreatic Cancer"],"prefix":"10.1002","volume":"32","author":[{"given":"Suguru","family":"Yamada","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery Nagoya Central Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0625-1911","authenticated-orcid":false,"given":"Tsutomu","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Surgery and Science, Faculty of Medicine, Academic Assembly University of Toyama  Toyama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Oshima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Nagoya Central Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosuke","family":"Nomoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Nagoya Central Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiko","family":"Oshima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Nagoya Central Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masamichi","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akimasa","family":"Nakao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Nagoya Central Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800820340"},{"issue":"8","key":"e_1_2_8_3_1","first-page":"1090","article-title":"Lymph Node Metastasis in Carcinoma of the Body and Tail of the Pancreas","volume":"84","author":"Nakao A.","year":"1997","journal-title":"British Journal of Surgery"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199810000-00007"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199905000-00003"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2005.06.044"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-011-0466-6"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000384"},{"key":"e_1_2_8_9_1","volume-title":"Classification of Pancretic Carcinoma","author":"Japan Pancreas Society","year":"2017"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800820321"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2019.37.4_suppl.189"},{"key":"e_1_2_8_12_1","volume-title":"NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines)","author":"Network NCC","year":"2022"},{"issue":"5","key":"e_1_2_8_13_1","first-page":"426","article-title":"Isolated Pancreatectomy for Pancreatic Head Carcinoma Using Catheter Bypass of the Portal Vein","volume":"40","author":"Nakao A.","year":"1993","journal-title":"Hepato\u2010Gastroenterology"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.1092"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.11.014"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10388-015-0515-3"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrad138"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ags3.12731"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0000000000000288"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-020-09066-5"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14184409"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2024.03.012"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-016-1217-x"}],"container-title":["Journal of Hepato-Biliary-Pancreatic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jhbp.12179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T13:55:33Z","timestamp":1762610133000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jhbp.12179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,25]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1002\/jhbp.12179"],"URL":"https:\/\/doi.org\/10.1002\/jhbp.12179","archive":["Portico"],"relation":{},"ISSN":["1868-6974","1868-6982"],"issn-type":[{"value":"1868-6974","type":"print"},{"value":"1868-6982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,25]]},"assertion":[{"value":"2025-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}