{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T13:13:13Z","timestamp":1780405993683,"version":"3.54.1"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Purpose<\/jats:title><jats:p>The role and optimal timing of endoscopic retrograde cholangiopancreatography (ERCP) in acute biliary pancreatitis without cholangitis (ABPwoC) remains unclear. Using a large national database, we aimed to examine hospitalization outcomes of patients with ABPwoC as a function of the performance and timing of ERCP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective study of adult patients with ABPwoC utilizing the National Inpatient Sample from 2016\u20132017. Patients who underwent inpatient ERCP were stratified into performance: within 24, 24\u201348, 48\u201372, and &gt;72\u2009h of hospital admission. The primary outcome was all\u2010cause inpatient mortality as a function of the performance and timing of ERCP; secondary outcomes, including healthcare utilization, were assessed. Multivariate modeling was used to adjust for potential confounders. Statistical analyses were conducted using STATA, version 16.0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 70\u2009030 patients with ABPwoC, 31.37% underwent inpatient ERCP. Performance (aOR: 0.6, <jats:italic>p<\/jats:italic>\u00a0&lt;\u2009.05), but not timing (aOR: 0.98, <jats:italic>p<\/jats:italic>\u00a0=\u2009.9), of inpatient ERCP was associated with significantly lower all\u2010cause inpatient mortality. Urgent ERCP (within 24\u2009h) was associated with shorter hospital length of stay, lower charges and cost, and less need for pancreatic drainage procedures, while ERCP within 72\u2009h was associated with less frequent intensive care unit admission (all <jats:italic>p<\/jats:italic>\u00a0&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Based on this large, nationwide analysis, inpatient ERCP for ABPwoC is associated with lower all\u2010cause mortality. ERCP within 24 and 72\u2009h, though not associated with lower mortality, are associated with multiple improved clinical outcomes, including lower healthcare charges and costs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.1285","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T08:08:52Z","timestamp":1669795732000},"page":"767-776","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The role and timing of endoscopic retrograde cholangiopancreatography in acute biliary pancreatitis without cholangitis: A nationwide analysis"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0796-6217","authenticated-orcid":false,"given":"Simcha","family":"Weissman","sequence":"first","affiliation":[{"name":"Department of Medicine Hackensack Meridian Health Palisades Medical Center  North Bergen New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachit","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Medicine The University of Toledo Medical Center  Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean","family":"Ehrlich","sequence":"additional","affiliation":[{"name":"Vatche &amp; Tamar Manoukian Division of Digestive Diseases David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Aziz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The University of Toledo Medical Center  Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2133-2480","authenticated-orcid":false,"given":"Ayrton","family":"Bangolo","sequence":"additional","affiliation":[{"name":"Department of Medicine Hackensack Meridian Health Palisades Medical Center  North Bergen New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amulya","family":"Gade","sequence":"additional","affiliation":[{"name":"Department of Medicine Hackensack Meridian Health Palisades Medical Center  North Bergen New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Thompson\u2010Edwards","sequence":"additional","affiliation":[{"name":"Department of Medicine Hackensack Meridian Health Palisades Medical Center  North Bergen New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kushaghar","family":"Singla","sequence":"additional","affiliation":[{"name":"Department of Medicine Hackensack Meridian Health Palisades Medical Center  North Bergen New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harini K.","family":"Venkatesh","sequence":"additional","affiliation":[{"name":"Department of Medicine Hackensack Meridian Health Palisades Medical Center  North Bergen New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mishka","family":"Hoo Kim","sequence":"additional","affiliation":[{"name":"Department of Medicine Hackensack Meridian Health Palisades Medical Center  North Bergen New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkata A. 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