{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T18:28:51Z","timestamp":1749061731689,"version":"3.40.5"},"reference-count":29,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T00:00:00Z","timestamp":1670889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Purpose<\/jats:title><jats:p>Donor\u2010type ABO blood group antigens (dABOAgs) have been detected in ABO\u2010incompatible adult living donor liver transplantation (ABOi ALDLT) grafts, but their fate and role in ABOi ALDLT rejection remain uncertain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The 0\u2010day, &lt;1\u2010month, and 1\u2010year serial liver graft biopsies from 30 ABOi ALDLT recipients were retrospectively evaluated. ABO antigen expression was quantitatively and serially measured by the mean number of positively stained vascular structures (endothelium of the capillaries, arteries, hepatic veins, and portal veins) within the portal tracts (sS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The dABOAg sS counts of 0\u2010day, &lt;1\u2010month, and 1\u2010year liver graft biopsies (32.3, 20.8, and 20.6, respectively) decreased significantly (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Early rejection in the &lt;1\u2010month biopsy was observed in 8\/30 (26.7%) recipients, four (13.3%) of whom showed antibody\u2010mediated rejection. The sS counts tended to rebound in grafts showing early rejection, with minimal changes from the 0\u2010day to &lt;1\u2010month period, but increased to pre\u2010transplantation levels after 1\u00a0year, compared to that in grafts without early rejection (36.0, 20.4, 19.6 vs. 23.7, 21.9, 23.0, respectively; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.040).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>While dABOAg expression decreased after ABOi ALDLT, recipients showing early rejection showed sustained graft dABOAg expression. Therefore, dABOAg expression may be involved in the mechanism of accommodation in ABOi transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.1291","type":"journal-article","created":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T08:56:12Z","timestamp":1669971372000},"page":"871-881","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The fate of donor\u2010type <scp>ABO<\/scp> blood group antigen expression in liver grafts in <scp>ABO<\/scp>\u2010incompatible adult living donor liver transplantation"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8939-1735","authenticated-orcid":false,"given":"Moon Young","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Surgery Seoul National University College of Medicine  Seoul Republic of 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